Derqaoui Sabrine, Elouazzani Hafsa, Boujida Ismail, Sayad Zahra, Zouaidia Fouad, Cherradi Nadia
Department of Pathology, Ibn Sina Teaching Hospital, Rabat, Morocco.
Mohamed V University, Rabat, Morocco.
Clin Med Insights Case Rep. 2021 Nov 23;14:11795476211060177. doi: 10.1177/11795476211060177. eCollection 2021.
Squamous cell carcinoma is the most common mucosal malignancy of the head and neck. Adenoid pseudo-angiosarcomatous SCC is a rare variant occurring commonly in the skin of the head and neck. However, involvement of oral cavity is extremely rare, with only few case reports in the English literature. Morphologically, the tumor shows marked acantholysis, with anastomozing channels mimicking vascular neoplasms. This variant represents a diagnostic challenge for pathologists, and immunohistochemical analysis remains essential for an accurate diagnosis. Herein, we describe the case of a pseudovascular SCC of the oral cavity in a 67 years old man with a brief revue of the literature to raise awareness on this rare variant; presenting diagnostic difficulties.
鳞状细胞癌是头颈部最常见的黏膜恶性肿瘤。腺样假血管肉瘤样鳞状细胞癌是一种罕见的变体，常见于头颈部皮肤。然而，口腔受累极为罕见，英文文献中仅有少数病例报告。形态学上，肿瘤表现出明显的棘层松解，伴有类似血管肿瘤的吻合通道。这种变体对病理学家来说是一个诊断挑战，免疫组化分析对于准确诊断仍然至关重要。在此，我们描述了一名67岁男性口腔假血管性鳞状细胞癌的病例，并简要回顾文献以提高对这种罕见变体的认识，其存在诊断困难。
