Chou Jen-Wei, Chung Chen-Shuan, Huang Tien-Yu, Tu Chia-Hung, Chang Chen-Wang, Chang Chung-Hsin, Wang Yen-Po, Hsu Wen-Hung, Yen Hsu-Heng, Kuo Chia-Jung, Chuang Chiao-Hsiung, Lin Ching-Pin, Tsai Tzung-Jiun, Su Ming-Yao, Wang Horng-Yuan, Wu Deng-Chyang, Chiu Cheng-Tang
Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Taiwan Association for the Study of Small Intestinal Diseases (TASSID), Taoyuan, Taiwan.
Gastroenterol Res Pract. 2021 Nov 18;2021:9574737. doi: 10.1155/2021/9574737. eCollection 2021.
Patients with Meckel's diverticulum (MD) are difficult to preoperatively diagnose because of its endoscopic inaccessibility. Balloon-assisted enteroscopy (BAE) allows endoscopic access to the entire small intestine. The aim of the current study was to investigate patients with MD diagnosed by BAE in Taiwan.
We conducted a retrospective, multicenter study of patients with MD who were diagnosed by BAE in Taiwan. The clinical characteristics, endoscopic features, histopathological findings, treatment methods, and outcomes were analyzed.
A total of 55 patients with MD were enrolled (46 males and 9 females). The mean age at diagnosis was 34.1 years. Overt gastrointestinal bleeding (87.3%) was the primary indication for BAE, followed by abdominal pain (9.1%), suspected small bowel tumor (1.8%), and Crohn's disease follow-up (1.8%). The mean distance between the ileocecal valve and MD was 71.6 cm (regarding diagnostic yields: BAE-100%, capsule endoscopy-40%, Meckel's scan-35.7%, computed tomography-14.6%, small bowel series-12.5%, and angiography-11.1%; regarding endoscopic features of MD: a large ostium-89.1%, a small ostium-7.3%, and a polypoid mass-3.6%). Surgical treatment was performed in 76.4% patients, and conservative treatment was performed in 23.6% patients. The mean length of MD in 42 patients who underwent surgical resection was 5.2 cm (in 43 patients of MD with available histopathology: heterotopic gastric tissue, 42.4%, heterotopic gastric and pancreatic tissues, 7%; heterotopic pancreatic tissue, 4.7%; heterotopic colonic tissue, 2.3%; and a neuroendocrine tumor, 2.3%).
The current study showed BAE is a very useful modality for detecting MD compared with other conventional modalities.
梅克尔憩室(MD)患者因内镜难以到达,术前诊断困难。气囊辅助小肠镜检查(BAE)可实现对整个小肠的内镜检查。本研究旨在调查台湾地区经BAE诊断为MD的患者。
我们对台湾地区经BAE诊断为MD的患者进行了一项回顾性多中心研究。分析了患者的临床特征、内镜特征、组织病理学结果、治疗方法及预后。
共纳入55例MD患者(男性46例,女性9例)。诊断时的平均年龄为34.1岁。显性胃肠道出血(87.3%)是BAE的主要指征,其次是腹痛(9.1%)、疑似小肠肿瘤(1.8%)和克罗恩病随访(1.8%)。回盲瓣与MD之间的平均距离为71.6 cm(诊断率方面:BAE为100%,胶囊内镜为40%,梅克尔扫描为35.7%,计算机断层扫描为14.6%,小肠造影为12.5%,血管造影为11.1%;MD的内镜特征方面:大开口占89.1%,小开口占7.3%,息肉样肿物占3.6%)。76.4%的患者接受了手术治疗,23.6%的患者接受了保守治疗。42例行手术切除的患者中MD的平均长度为5.2 cm(43例有组织病理学结果的MD患者中:异位胃组织占42.4%,异位胃和胰腺组织占7%,异位胰腺组织占4.7%,异位结肠组织占2.3%,神经内分泌肿瘤占2.3%)。
本研究表明,与其他传统方法相比,BAE是检测MD的一种非常有用的方法。