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飞秒激光辅助的同种异体附加基质角膜移植术联合或不联合准分子激光供体角膜磨镶术治疗圆锥角膜

Femtosecond Laser-assisted Allogenic Additive Stromal Keratoplasty With or Without Excimer Laser Donor Keratomileusis for Management of Keratoconus.

作者信息

Jafarinasab Mohammad-Reza, Hadi Yasaman, Espandar Goldis

机构信息

Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

出版信息

J Ophthalmic Vis Res. 2021 Oct 25;16(4):691-697. doi: 10.18502/jovr.v16i4.9761. eCollection 2021 Oct-Dec.

Abstract

We describe a modified allogenic intrastromal lenticule implantation technique for management of keratoconus (KCN). Patients with advanced KCN already scheduled for corneal transplantation were enrolled. An allogenic corneal lenticule was implanted inside a stromal pocket created by femtosecond laser. In three cases, the estimated refractive error of the recipient eyes was corrected on the donor lenticules using an Excimer laser. All operated eyes underwent corneal crosslinking at the time of surgery. This method was named "Femtosecond Laser-assisted Allogenic Stromal Keratoplasty Without and With Excimer Laser-assisted Donor Keratomileusis"; briefly called FASK and FASK Plus EDK, respectively. Two out of five patients were satisfied with the results. There was a decrease in the average simulated keratometric values as well as myopia when FASK Plus EDK was performed. Increased corneal thickness was achieved in all cases. Graft edema gradually decreased over weeks but interface wrinkling and lenticule folds in the visual axis remained as a problem during follow-up period. No other complications were encountered.

摘要

我们描述了一种用于治疗圆锥角膜(KCN)的改良同种异体基质内透镜植入技术。招募了已安排进行角膜移植的晚期KCN患者。将同种异体角膜透镜植入飞秒激光创建的基质袋内。在三例病例中,使用准分子激光在供体透镜上矫正了受体眼的预估屈光不正。所有手术眼在手术时均接受了角膜交联。该方法被命名为“有和没有准分子激光辅助供体角膜磨镶术的飞秒激光辅助同种异体基质角膜移植术”;简称为FASK和FASK Plus EDK。五分之二的患者对结果满意。进行FASK Plus EDK时,平均模拟角膜曲率值以及近视度数均有所降低。所有病例均实现了角膜厚度增加。移植水肿在数周内逐渐减轻,但随访期间视轴上的界面皱纹和透镜褶皱仍然是一个问题。未遇到其他并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b5f/8593540/096dc6871d7a/jovr-16-691-g001.jpg

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