Pathology Department, Wuhan Hanyang Hospital, Wuhan, Hubei 430050, China.
Emergency Medicine, Wuhan No. 1 Hospital, Wuhan, Hubei 430022, China.
J Healthc Eng. 2021 Nov 19;2021:3927828. doi: 10.1155/2021/3927828. eCollection 2021.
One of the most common malignant tumors of the digestive tract is emergency colorectal cancer. In recent years, both morbidity and mortality rates, particularly in our country, are getting higher and higher. At present, diagnosis of colorectal cancer, specifically in the emergency department of a hospital, is based on the doctor's pathological diagnosis, and it is heavily dependent on the doctor's clinical experience. The doctor's workload is heavy, and misdiagnosis events occur from time to time. Therefore, computer-aided diagnosis technology is desperately needed for colorectal pathological images to assist pathologists in reducing their workload, improve the efficiency of diagnosis, and eliminate misdiagnosis. To address these issues, a gland segmentation of emergency colorectal pathology images and diagnosis of benign and malignant pathology is presented in this paper. Initially, a multifeatured auxiliary diagnosis is designed to enable diagnosis of benign and malignant diagnosis of emergency colorectal pathology. The proposed algorithm constructs an SVM-enabled pathological diagnosis model which is based on contour, color, and texture features. Additionally, their combination is used for pathological benign and malignant pathological diagnosis of two types of data sets D1 (original pathological image dataset) and D2 (dataset that has undergone glandular segmentation) diagnosis. Experimental results show that the proposed pathological diagnosis model has higher diagnostic accuracy on D2. Among these datasets, SVM based on the multifeature fusion of contour and texture achieved the highest diagnostic accuracy rate, i.e., 83.75%, which confirms that traditional image processing methods have limitations. Diagnosing benign and malignant colorectal pathology in an emergency is more difficult and must be treated on a priority basis. Finally, an emergency colorectal pathology diagnosis method, which is based on deep convolutional neural networks such as CIFAR and VGG, is proposed. After configuring and training process of the two networks, trained CIFAR and VGG network models are applied to the diagnosis of both datasets, i.e., D1 and D2, respectively.
消化道最常见的恶性肿瘤之一是急症结直肠癌。近年来,无论是发病率还是死亡率,特别是在我国,都越来越高。目前,结直肠癌的诊断,特别是在医院的急诊科,是基于医生的病理诊断,并且严重依赖医生的临床经验。医生的工作量大,误诊事件时有发生。因此,迫切需要计算机辅助诊断技术来辅助病理医生对结直肠病理图像进行诊断,以减少医生的工作量,提高诊断效率,消除误诊。针对这些问题,本文提出了一种用于急症结直肠病理图像的腺体分割和良恶性病理诊断的方法。首先,设计了一种多特征辅助诊断方法,用于诊断急症结直肠的良恶性。所提出的算法构建了一个基于轮廓、颜色和纹理特征的支持向量机病理诊断模型。此外,还将它们的组合用于两种数据集 D1(原始病理图像数据集)和 D2(经过腺体分割的数据集)的良恶性病理诊断。实验结果表明,所提出的病理诊断模型在 D2 上具有更高的诊断准确性。在这些数据集中,基于轮廓和纹理多特征融合的 SVM 达到了最高的诊断准确率,即 83.75%,这证实了传统图像处理方法存在局限性。诊断急症结直肠的良恶性更为困难,必须优先处理。最后,提出了一种基于 CIFAR 和 VGG 等深度卷积神经网络的急症结直肠病理诊断方法。对这两个网络进行配置和训练过程后,将训练好的 CIFAR 和 VGG 网络模型分别应用于数据集 D1 和 D2 的诊断。