Ayoub Kusay, Kanjo Samir, Swed Sarya, Chawa Yamane, Alswij Mahmoud Alhamadeh, Mahli Nihad
Department of General Surgery, University Aleppo Hospital, Aleppo, Syria.
Faculty of Human Medicine, University Aleppo, Aleppo, Syria.
Ann Med Surg (Lond). 2021 Nov 3;71:103011. doi: 10.1016/j.amsu.2021.103011. eCollection 2021 Nov.
Familial Mediterranean fever (FMF) is an autosomal recessive auto-inflammatory disorder characterized mainly by brief recurrent episodes of peritonitis, pleuritis, and arthritis, usually with accompanying fever. Almost all patients with FMF experience abdominal episodes. Abdominal pain develops, and may progress to peritonitis. Intestinal obstruction secondary to adhesions may be observed in FMF patients but this is the first case from Syria. A 17-year-old Syrian female patient presented to our hospital complaining of abdominal pain, frequent vomiting, weight loss and absolute constipation in the past ten days, with a confirmation of her infecting by FMF 3 years ago. The obstruction was treated conservatively and after 6 months we had to treat the obstruction by laparoscopic releasing of abdominal bands as a result of recurrence. The patient was discharged and followed up for 6 months with excellent results. We herein report the first known case of FMF with small bowel obstruction in Syria with delayed in diagnosis. Physicians should be alert to this possible complication when FMF patients arrive at the emergency room.
家族性地中海热（FMF）是一种常染色体隐性自身炎症性疾病，主要特征为腹膜炎、胸膜炎和关节炎反复发作，通常伴有发热。几乎所有FMF患者都会经历腹部发作。腹痛出现，并可能发展为腹膜炎。FMF患者可能会出现粘连所致的肠梗阻，但这是叙利亚的首例此类病例。一名17岁的叙利亚女性患者因腹痛、频繁呕吐、体重减轻及过去十天完全便秘前来我院就诊，该患者三年前确诊感染FMF。肠梗阻最初采用保守治疗，6个月后因复发不得不通过腹腔镜松解腹部束带来治疗。患者出院并随访6个月，效果良好。我们在此报告叙利亚首例已知的FMF合并小肠梗阻且诊断延迟的病例。当FMF患者前往急诊室时，医生应警惕这种可能的并发症。
