Guo Yulin, Hu Shun, Wang Shuo, Li Ang, Cao Feng, Li Fei
Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Research and Development Department, Sinovac Biotech Ltd, Beijing 100053, China.
Emerg Med Int. 2021 Nov 17;2021:7586338. doi: 10.1155/2021/7586338. eCollection 2021.
Surgical interventions for pancreatic pseudocyst (PP) are traditionally managed by an open surgical approach. With the development of minimally invasive surgical techniques, a laparoscopic surgical approach for PPs has been conducted increasingly with comparable outcomes. The present study was conducted to compare the efficacy and safety of surgical intervention for PPs between the laparoscopic approach and the open approach.
Databases including Cochrane Library, PubMed, and EMBASE were searched to identify studies that compared the safety and efficacy of surgical intervention for PPs between the laparoscopic approach and the open approach (until Aug 1st 2020).
A total of 6 studies were eligible in qualitative synthesis. The laparoscopic approach was associated with less intraoperative blood loss (MD = -69.97; 95% CI: -95.14 to -44.70, < 0.00001; =0.86 for heterogeneity) and shorter operating time (MD = -33.12; 95% CI: -62.24 to -4.00, =0.03; < 0.00001 for heterogeneity). There was no significant difference found between the two approaches regarding the success rate and the recurrence rate. The postoperative complications and mortality rates were comparable between the two approaches.
The laparoscopic approach for the surgical intervention of PPs is safe and efficacious with shorter-term benefits.
胰腺假性囊肿（PP）的外科干预传统上采用开放手术方法。随着微创外科技术的发展，PP的腹腔镜手术方法越来越多地被采用，且疗效相当。本研究旨在比较腹腔镜手术和开放手术对PP进行外科干预的疗效和安全性。
检索包括Cochrane图书馆、PubMed和EMBASE在内的数据库，以识别比较腹腔镜手术和开放手术对PP进行外科干预的安全性和疗效的研究（截至2020年8月1日）。
共有6项研究符合定性综合分析的条件。腹腔镜手术方法术中失血量较少（MD=-69.97；95%CI：-95.14至-44.70，<0.00001；异质性I²=0.86），手术时间较短（MD=-33.12；95%CI：-62.24至-4.00，P=0.03；异质性I²<0.00001）。两种手术方法在成功率和复发率方面无显著差异。两种手术方法术后并发症和死亡率相当。
腹腔镜手术干预PP安全有效，具有短期优势。
