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同步口腔黏膜和骨内口腔癌:罕见隐匿性第二原发恶性肿瘤病例报告。

Synchronous mucosal and intraosseous oral cavity carcinomas: a case of rare occult second primary malignancy.

机构信息

Lancashire Teaching Hospitals NHS Foundation Trust, UK.

出版信息

Ann R Coll Surg Engl. 2022 May;104(5):e150-e152. doi: 10.1308/rcsann.2021.0203. Epub 2021 Nov 29.

Abstract

Secondary primary malignancies within the head and neck region are well documented. Within this group, synchronous tumours with an index oral cancer are usually found in the oropharyngeal or laryngeal sites. We present a rare case of an index squamous cell carcinoma in the tongue with a synchronous primary intraosseous squamous cell carcinoma. We discuss the challenges associated with investigation, diagnosis and subsequent management. Treatment aims remain the same; namely, eradicating the disease using surgery, radiotherapy, chemotherapy or a combination of these modalities. It is important to acknowledge the unpredictable pattern of tumour presentation and the need to maintain a high index of suspicion.

摘要

头颈部区域的次级原发性恶性肿瘤已有充分的记载。在这组肿瘤中,与口腔癌同时发生的肿瘤通常位于口咽或喉部位。我们报告了一例罕见的舌部原发性鳞状细胞癌伴同时性原发性骨内鳞状细胞癌的病例。我们讨论了与调查、诊断和后续管理相关的挑战。治疗目标仍然是相同的,即通过手术、放疗、化疗或这些方法的联合使用来消灭疾病。重要的是要认识到肿瘤表现的不可预测模式以及保持高度怀疑的必要性。

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