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1
Synchronous mucosal and intraosseous oral cavity carcinomas: a case of rare occult second primary malignancy.同步口腔黏膜和骨内口腔癌:罕见隐匿性第二原发恶性肿瘤病例报告。
Ann R Coll Surg Engl. 2022 May;104(5):e150-e152. doi: 10.1308/rcsann.2021.0203. Epub 2021 Nov 29.
2
A role for panendoscopy? Second primary tumour in early stage squamous cell carcinoma of the oral tongue.全内镜检查有作用吗?早期舌鳞状细胞癌中的第二原发性肿瘤。
J Laryngol Otol. 2015 Jan;129 Suppl 1:S27-31. doi: 10.1017/S0022215114002989.
3
[The indication of panendoscopy in the search for synchronous and metachronous head and neck cancer].[全内镜检查在寻找同时性和异时性头颈癌中的应用指征]
Rev Med Suisse. 2013 Oct 2;9(400):1770, 1772-4.
4
Panendoscopy and synchronous second primary tumors in head and neck cancer patients.头颈部癌患者的全内镜检查与同步性第二原发肿瘤
Eur Arch Otorhinolaryngol. 2005 Jan;262(1):17-20. doi: 10.1007/s00405-004-0743-y. Epub 2004 Mar 5.
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[Second carcinomas in cancers of the mouth cavity, pharynx and larynx. Clinical, histopathologic and cell kinetic findings].[口腔、咽及喉癌中的第二原发癌。临床、组织病理学及细胞动力学研究结果]
Laryngorhinootologie. 2000 Aug;79(8):478-82. doi: 10.1055/s-2000-5908.
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Prevalence of Synchronous ESCN in Head and Neck Cancer: A Single-Institution Perspective.头颈部癌症中同步 ESCN 的流行率:单机构视角。
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[Early detection of multiple tumors in primary diagnosis of oral carcinomas using panendoscopy].[使用全内镜检查在口腔癌初步诊断中早期检测多种肿瘤]
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[Current practice of tumour endoscopy in German ENT-clinics].
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本文引用的文献

1
Multiple concomitant oral cavity cancers: Incidence, management, and outcomes.多发同时性口腔癌:发病率、治疗及预后
J Surg Oncol. 2017 Jun;115(7):835-841. doi: 10.1002/jso.24600. Epub 2017 Mar 20.
2
Clinicopathological Study of Primary Intraosseous Squamous Cell Carcinoma of the Jaw and a Review of the Literature.颌骨原发性骨内鳞状细胞癌的临床病理研究及文献复习
J Oral Maxillofac Surg. 2016 Dec;74(12):2420-2427. doi: 10.1016/j.joms.2016.05.006. Epub 2016 May 18.
3
Oral field cancerization: an update on current concepts.口腔场癌化:当前概念的更新
Oncol Rev. 2014 Jun 30;8(1):244. doi: 10.4081/oncol.2014.244. eCollection 2014 Mar 17.
4
Clinical characteristics of multiple primary carcinomas of the oral cavity.口腔多原发性癌的临床特征
Oral Oncol. 2015 Feb;51(2):182-9. doi: 10.1016/j.oraloncology.2014.11.013. Epub 2014 Dec 10.
5
Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries.头颈癌患者发生第二原发性癌症的风险:13个癌症登记处的汇总分析。
Int J Cancer. 2008 Nov 15;123(10):2390-6. doi: 10.1002/ijc.23798.
6
Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin.口腔复层鳞状上皮中的场癌化;多中心起源的临床意义。
Cancer. 1953 Sep;6(5):963-8. doi: 10.1002/1097-0142(195309)6:5<963::aid-cncr2820060515>3.0.co;2-q.
7
Synchronous and metachronous head and neck carcinomas.同步性和异时性头颈部癌
Cancer. 1994 Oct 1;74(7):1933-8. doi: 10.1002/1097-0142(19941001)74:7<1933::aid-cncr2820740718>3.0.co;2-x.

同步口腔黏膜和骨内口腔癌:罕见隐匿性第二原发恶性肿瘤病例报告。

Synchronous mucosal and intraosseous oral cavity carcinomas: a case of rare occult second primary malignancy.

机构信息

Lancashire Teaching Hospitals NHS Foundation Trust, UK.

出版信息

Ann R Coll Surg Engl. 2022 May;104(5):e150-e152. doi: 10.1308/rcsann.2021.0203. Epub 2021 Nov 29.

DOI:10.1308/rcsann.2021.0203
PMID:34841900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10335049/
Abstract

Secondary primary malignancies within the head and neck region are well documented. Within this group, synchronous tumours with an index oral cancer are usually found in the oropharyngeal or laryngeal sites. We present a rare case of an index squamous cell carcinoma in the tongue with a synchronous primary intraosseous squamous cell carcinoma. We discuss the challenges associated with investigation, diagnosis and subsequent management. Treatment aims remain the same; namely, eradicating the disease using surgery, radiotherapy, chemotherapy or a combination of these modalities. It is important to acknowledge the unpredictable pattern of tumour presentation and the need to maintain a high index of suspicion.

摘要

头颈部区域的次级原发性恶性肿瘤已有充分的记载。在这组肿瘤中,与口腔癌同时发生的肿瘤通常位于口咽或喉部位。我们报告了一例罕见的舌部原发性鳞状细胞癌伴同时性原发性骨内鳞状细胞癌的病例。我们讨论了与调查、诊断和后续管理相关的挑战。治疗目标仍然是相同的,即通过手术、放疗、化疗或这些方法的联合使用来消灭疾病。重要的是要认识到肿瘤表现的不可预测模式以及保持高度怀疑的必要性。