Am J Trop Med Hyg. 2021 Nov 29;106(2):623-625. doi: 10.4269/ajtmh.21-0943.
Epstein-Barr virus (EBV) is the most common cause of infectious mononucleosis (IM) and IM is a clinical syndrome typically characterized by fever, pharyngitis, and cervical lymph node enlargement. We describe the case of a 19-year-old man with IM complicated by splenic infarction. The patient visited our hospital because of upper abdominal pain without a fever and sore throat. Abdominal computed tomography revealed a low-density area in the spleen, which indicated splenic infarction. The next day, he developed a fever. After diminishing abdominal pain and fever, he developed pharyngitis accompanied by fever. Acute EBV infection was confirmed by serological tests. The patient was successfully managed with no specific therapy. Splenic infarction is a rare complication of IM and this case showed that splenic infarction can precede a fever and pharyngitis.
EB 病毒（EBV）是传染性单核细胞增多症（IM）最常见的原因，IM 是一种临床综合征，通常以发热、咽炎和颈淋巴结肿大为特征。我们描述了一例 IM 合并脾梗死的 19 岁男性患者。患者因上腹痛、无发热和咽痛就诊于我院。腹部 CT 显示脾脏低密度区，提示脾梗死。次日，他出现发热。腹痛和发热消退后，他出现咽炎伴发热。血清学检查证实为急性 EBV 感染。患者未接受特异性治疗，病情成功缓解。脾梗死是 IM 的罕见并发症，本例表明脾梗死可先于发热和咽炎发生。
