Singhal Adit, Suchman Kelly I, Rhee Aaron, Patel Himanshu, Paracha Awais, Agrawal Vedika, Cohen Jessica
Internal Medicine, Northwell Health, New Hyde Park, USA.
Gastroenterology, Northwell Health, New Hyde Park, USA.
Cureus. 2024 Apr 16;16(4):e58414. doi: 10.7759/cureus.58414. eCollection 2024 Apr.
Splenic infarction is a rare and likely underdiagnosed complication of Epstein-Barr virus (EBV)-associated infectious mononucleosis (IM). Here, we describe an 18-year-old Guyanese male with persistent severe left-sided abdominal pain found to be EBV positive and have a large splenic infarct, along with a transient decrease in protein C, protein S, and antithrombin III activity levels. He was treated with supportive care and anticoagulated with heparin and apixaban. We review prior reports and perspectives on underlying pathophysiology, diagnosis, and the management of these cases, which likely do not require anticoagulation but may be considered on a per-case basis.
脾梗死是一种与爱泼斯坦-巴尔病毒（EBV）相关的传染性单核细胞增多症（IM）罕见且可能诊断不足的并发症。在此，我们描述一名18岁的圭亚那男性，他因持续严重的左侧腹痛被发现EBV呈阳性，并有大面积脾梗死，同时蛋白C、蛋白S和抗凝血酶III活性水平短暂下降。他接受了支持性治疗，并使用肝素和阿哌沙班进行抗凝治疗。我们回顾了先前关于这些病例潜在病理生理学、诊断和管理的报告及观点，这些病例可能不需要抗凝治疗，但可根据具体情况考虑。
