Dheir Hamad, Güngör Özkan, Ulu Memnune Sena, Gök Oğuz Ebru, Eren Necmi, Altunören Orçun, Tatar Erhan, Atilgan Kadir Gökhan, Karaköse Süleyman, Güney Ibrahim, Eroğlu Eray, Mutluay Rüya, Bozaci Ilter, Alp Alper, Akdam Hakan, Seziş Demirci Meltem, Soypaçaci Zeki, Akarsu Özger, Paydaş Saime, Ercan Zafer, Kara Ekrem, Topal Cevat, Yavaş Haldun Hakan, Tekkarişmaz Nihan, Turgutalp Kenan, Hüzmeli Can, Inci Ayça, Karaveli Gürsoy Güner, Güneş Keskin Ayşe Jini, Huddam Bülent, Hür Ender, Yildiz Abdulmecit, Bekfilavioğlu Garip, Şahutoğlu Tuncay, Tuncay Mehmet, Bardak Simge, Bakirdöğen Serkan, Yilmaz Zülfükar, Günay Emrah, Tunca Onur, Kazan Sinan, Pembegül Yiğit Irem, Saritaş Hazen, Sevinç Can, Kaptanoğullari Hakan, Gökçay Bek Sibel, Kurultak Ilhan, Değirmenci Ali, Şakaci Murat, Kiliç Ilhan, Aydin Zeki, Çolak Hülya, Dervişoğlu Erkan, Şahin Garip, Ayli Mehmet Deniz, Sipahi Savaş, Derici Ülver
Turk J Med Sci. 2021 Nov 30;52(2):354-60. doi: 10.3906/sag-2106-120.
BACKGROUND/AIM: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients.
Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded.
In this study, we reached 9038 HD female patients? data in the study. A total of 235 pregnancies were detected in 145 patients. The mean age was 35.42 (35 ± 7.4) years. The mean age at first gestation was 30.8 ± 6.5 years. The average birth week was 32 (28 - 36) weeks. 53.8% (no = 78) of the patients had live birth, 51.7% (no = 70) had at least one abortion in the first 20 weeks, and 13.1% (no = 19) had at least one stillbirth after 20 weeks. The rate of patients' increased numbers of dialysis sessions during pregnancy was 71.7%. The abortion rate was 22.4% in those with increased HD sessions, whereas 79.3% in those not increased HD sessions (p < 0.001). Live birth frequency was 67.2% in the increased HD sessions group and 3.4% in those who did not differ in HD sessions (p < 0.001).
For the first time, we reported pregnancy outcomes in HD female patients, covering all regions of Turkey. It has been observed that; increasing the number of HD sessions in dialysis patients will decrease fetal and maternal complications and increase live birth rates.
背景/目的：本研究旨在调查血液透析（HD）患者的妊娠频率，并评估影响活产的因素。
对2014年1月1日至2019年12月31日期间回顾性报告妊娠情况的女性HD患者进行研究。记录HD时长、原发疾病、妊娠是否导致流产、死产或活产、诊断妊娠后HD时长是否延长以及是否伴有先兆子痫。
在本研究中，我们获取了9038名HD女性患者的数据。共检测到145例患者有235次妊娠。平均年龄为35.42（35±7.4）岁。首次妊娠的平均年龄为30.8±6.5岁。平均分娩孕周为32（28 - 36）周。53.8%（n = 78）的患者活产，51.7%（n = 70）的患者在孕20周前至少有一次流产，13.1%（n = 19）的患者在孕20周后至少有一次死产。妊娠期间患者透析次数增加的比例为71.7%。HD次数增加者的流产率为22.4%，而HD次数未增加者为79.3%（p < 0.001）。HD次数增加组的活产频率为67.2%，HD次数无差异组为3.4%（p < 0.001）。
我们首次报告了覆盖土耳其所有地区的HD女性患者的妊娠结局。据观察，增加透析患者的HD次数将减少母婴并发症并提高活产率。
