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巴西南部家庭农民职业性暴露于农药与超重和腹型肥胖的关联。

Association of occupational exposure to pesticides with overweight and abdominal obesity in family farmers in southern Brazil.

机构信息

Postgraduate Program in Food, Nutrition and Health - Universidade Federal Do Rio Grande Do Sul - UFRGS, Porto Alegre, Brazil.

Institute of Collective Health /ISC Universidade Federal da Bahia - UFBA, Salvador, Brazil.

出版信息

Int J Environ Health Res. 2022 Dec;32(12):2798-2809. doi: 10.1080/09603123.2021.1991284. Epub 2021 Nov 30.

Abstract

The association of chronic exposure to pesticides with overweight and abdominal obesity in adult farmers was investigated. This cross-sectional study included a random sample of 122 farmers and their family members of both sexes (61% were male), living in the municipality of Farroupilha, southern Brazil. Pesticide groups and their individual compounds were self-reported and classified according to major functional and chemical classes (never used, 1-20 years, or > 20 years of use). Abdominal obesity and overweight were the outcomes of interest. A multivariate Poisson regression model was analyzed. After confounding factors were controlled, chronic use (>20 years) of insecticides (PR: 1.45; 95% CI: 1.00-2.10) and organophosphorus pesticides (PR: 1.48, 95% CI: 1.02-2.12) was associated with a higher prevalence of overweight but not abdominal obesity. Additional studies are needed to confirm our findings and clarify the specific mechanisms of these pollutants in the etiology of obesity.

摘要

本研究旨在探讨成年农民长期接触农药与超重和腹型肥胖的相关性。该横断面研究纳入了巴西南部法鲁皮拉市的 122 名农民及其家庭成员(其中 61%为男性)作为随机样本。根据主要功能和化学类别(从未使用、使用 1-20 年或 >20 年),自行报告并分类了农药类别及其单个化合物。腹型肥胖和超重是本研究的主要结局。采用多变量泊松回归模型进行分析。在控制混杂因素后,慢性使用(>20 年)杀虫剂(PR:1.45;95%CI:1.00-2.10)和有机磷农药(PR:1.48,95%CI:1.02-2.12)与超重的患病率增加相关,但与腹型肥胖无关。需要进一步的研究来证实我们的发现,并阐明这些污染物在肥胖发病机制中的具体作用机制。

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