Faculty of Nursing, Naresuan University, Phitsanulok, 65000, Thailand.
Faculty of Agriculture, Natural Resources and Environment, Naresuan University, Phitsanulok, 65000, Thailand.
F1000Res. 2023 Dec 5;10:474. doi: 10.12688/f1000research.53257.3. eCollection 2021.
Pesticide exposure has been suspected as a cause of rhinitis, a common disease that affects the health and well-being of millions of people around the world. This cross-sectional study aimed to examine the association between pesticide use and rhinitis prevalence among farmers in Phitsanulok province, Thailand.
Data on historical pesticide use and rhinitis were collected by an in-person interview questionnaire. Data from 9,649 participants were included in the analysis. The association between pesticide exposure and rhinitis was determined by multiple variable logistic regression, adjusted for potential confounding factors.
The study found an association between pesticide exposure and the prevalence of rhinitis. The association was consistent across various types of pesticides (insecticides, herbicides, fungicides, rodenticides, and molluscicides) and individual pesticides. Some of the relationships were in a dose-response pattern. This finding was new as previous studies often reported the association of only a few specific pesticides.
The results from this large cross-sectional study supports existing literature on the potential effects of pesticides on rhinitis. In addition, the analysis showed that the rhinitis effect might be in fact related to the properties of the types of pesticides rather than individual chemical toxicity. The impact of pesticides on rhinitis should receive more attention from public health and other organizations responsible for the farmers' health.
农药暴露已被怀疑是导致鼻炎的原因之一,鼻炎是一种常见疾病,影响着全球数以百万计的人们的健康和福祉。本横断面研究旨在检验在泰国碧差汶府农民中,农药使用与鼻炎患病率之间的关系。
通过面对面访谈问卷收集历史农药使用和鼻炎的数据。对 9649 名参与者的数据进行了分析。通过多变量逻辑回归,调整潜在混杂因素,确定了农药暴露与鼻炎之间的关联。
研究发现农药暴露与鼻炎患病率之间存在关联。这种关联在各种类型的农药(杀虫剂、除草剂、杀菌剂、灭鼠剂和杀螺剂)和个别农药中都是一致的。一些关系呈剂量反应模式。这一发现是新的,因为以前的研究通常只报告了少数几种特定农药的关联。
这项大型横断面研究的结果支持了关于农药对鼻炎潜在影响的现有文献。此外,分析表明,鼻炎的影响实际上可能与农药类型的特性有关,而不是与个别化学毒性有关。农药对鼻炎的影响应引起公共卫生和其他负责农民健康的组织的更多关注。