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埃塞俄比亚向性伴侣披露艾滋病毒血清阳性情况:一项系统综述。

Disclosure of HIV seropositivity to sexual partner in Ethiopia: A systematic review.

作者信息

Endalamaw Aklilu, Assefa Yibeltal, Geremew Demeke, Belete Habte, Dachew Berihun Assefa, Belachew Amare, Animaw Worku, Habtewold Tesfa Dejenie, Wilson Rhonda

机构信息

College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

School of Public Health, The University of Queensland, Brisbane, QLD, Australia.

出版信息

Womens Health (Lond). 2021 Jan-Dec;17:17455065211063021. doi: 10.1177/17455065211063021.

DOI:10.1177/17455065211063021
PMID:34844482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8640980/
Abstract

INTRODUCTION

In Ethiopia, the burden of HIV/AIDS is a public health issue that requires significant control of transmission. Once an infection has been established, determinants influence people living with HIV to disclose or not their HIV-positive status to sexual partners. This study assessed the proportion and associated factors of people living with HIV's disclosure status to sexual partners.

METHODS

CRD42020149092 is the protocol's registration number in the PROSPERO database. We searched PubMed, Scopus, African Journals Online, and Google Scholar databases. For the subjective and objective assessment of publication bias, we used a funnel plot and Egger's regression test, respectively. The statistic was used to assess variation across studies. Meta-analysis of weighted inverse variance random-effects model was used to estimate the pooled proportion. We conducted subgroup and sensitivity analyses to investigate the cause of heterogeneity and the impact of outliers on the overall estimation, respectively. A trend analysis was also performed to show the presence of time variation.

RESULTS

The percentage of people living with HIV who disclosed their HIV-positive status to sexual partners was 76.03% (95% confidence interval: 68.78, 83.27). Being on antiretroviral therapy (adjusted odds ratio = 6.19; 95% confidence interval: 2.92, 9.49), cohabiting with partner (adjusted odds ratio = 4.48; 95% confidence interval: 1.24, 7.72), receiving HIV counseling (adjusted odds ratio = 3.94; 95% confidence interval: 2.08, 5.80), having discussion prior to HIV testing (adjusted odds ratio = 4.40; 95% confidence interval: 2.11, 6.69), being aware of partner's HIV status (adjusted odds ratio = 6.08; 95% confidence interval: 3.05, 9.10), positive relationship with partner (adjusted odds ratio = 4.44; 95% confidence interval:1.28, 7.61), and being member of HIV association (adjusted odds ratio = 3.70; 95% confidence interval: 2.20, 5.20) had positive association with HIV status disclosure.

CONCLUSION

In Ethiopia, more than one-fourth of adults living with HIV did not disclose their HIV-positive status to sexual partners. HIV-positive status disclosure was influenced by psychosocial factors. A multidimensional approach is required to increase seropositive disclosure in Ethiopia.

摘要

引言

在埃塞俄比亚,艾滋病毒/艾滋病负担是一个公共卫生问题,需要大力控制传播。一旦感染确立,多种因素会影响艾滋病毒感染者是否向性伴侣披露其艾滋病毒阳性状态。本研究评估了艾滋病毒感染者向性伴侣披露状态的比例及相关因素。

方法

CRD42020149092是该方案在PROSPERO数据库中的注册号。我们检索了PubMed、Scopus、非洲期刊在线和谷歌学术数据库。对于发表偏倚的主观和客观评估,我们分别使用了漏斗图和Egger回归检验。采用统计量评估各研究间的差异。使用加权逆方差随机效应模型进行荟萃分析以估计合并比例。我们分别进行了亚组分析和敏感性分析,以调查异质性的原因和异常值对总体估计的影响。还进行了趋势分析以显示时间变化的存在。

结果

向性伴侣披露艾滋病毒阳性状态的艾滋病毒感染者比例为76.03%(95%置信区间:68.78,83.27)。接受抗逆转录病毒治疗(调整后的优势比=6.19;95%置信区间:2.92,9.49)、与伴侣同居(调整后的优势比=4.48;95%置信区间:1.24,7.72)、接受艾滋病毒咨询(调整后的优势比=3.94;95%置信区间:2.08,5.80)、在艾滋病毒检测前进行讨论(调整后的优势比=4.40;95%置信区间:2.11,6.6九)、知晓伴侣的艾滋病毒状态(调整后的优势比=6.08;95%置信区间:3.05,9.10)、与伴侣关系良好(调整后的优势比=4.44;95%置信区间:1.28,7.61)以及是艾滋病毒协会成员(调整后的优势比=3.70;95%置信区间:2.20,5.20)与艾滋病毒状态披露呈正相关。

结论

在埃塞俄比亚,超过四分之一的成年艾滋病毒感染者未向性伴侣披露其艾滋病毒阳性状态。艾滋病毒阳性状态的披露受社会心理因素影响。在埃塞俄比亚,需要采取多维度方法来增加血清阳性披露率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/d1cae3fbf0f8/10.1177_17455065211063021-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/8884f245ff71/10.1177_17455065211063021-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/2577a5a08252/10.1177_17455065211063021-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/0eda6743b49d/10.1177_17455065211063021-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/21a7fb0b45b7/10.1177_17455065211063021-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/d1cae3fbf0f8/10.1177_17455065211063021-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/8884f245ff71/10.1177_17455065211063021-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/2577a5a08252/10.1177_17455065211063021-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/0eda6743b49d/10.1177_17455065211063021-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/21a7fb0b45b7/10.1177_17455065211063021-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd04/8640980/d1cae3fbf0f8/10.1177_17455065211063021-fig5.jpg

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