Manchester Centre for Transplantation, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, Greater Manchester, M13 9WL, UK; Department of Hepatobiliary Surgery, Royal Blackburn Hospitals, Blackburn, Lancashire, BB2 3 HQ, UK.
Cardiff Transplant Unit, University Hospital of Wales, Cardiff, CF14 4XW, UK; Cardiff University, School of Medicine, Division of Infection and Immunity, Cardiff CF14 4XN, UK.
Surgeon. 2022 Oct;20(5):e273-e281. doi: 10.1016/j.surge.2021.09.006. Epub 2021 Nov 27.
This retrospective study was performed to analyse if laterality of the retrieved living donor kidney had any effect on donor and recipient outcomes after hand assisted laparoscopic donor nephrectomy (HALDN). 739 donors who underwent HALDN between January 2006 and January 2018 at a large tertiary transplant centre in the United Kingdom were included. Donor outcomes in individuals undergoing right versus left HALDN were compared with respect to conversion rates, morbidity, warm and cold ischaemia times and recipient failure rates, vascular and ureteric complications. 604 (81.7%) underwent left HALDN and 135 (18.3%) underwent right HALDN, mean age was 47.1 years and 46.8 years respectively with comparable gender distribution. The operative time was shorter for the left side (p = 0.003) and improved during the study for the left but not the right side. In recipients who received left kidneys there were more early technical failures observed (8 versus 1) though not statistically significant. Most centres prefer performing a left nephrectomy and recipient surgeons prefer a left kidney for transplantation primarily because of having a longer vein. This large study provides reassurance that right HALDN nephrectomy is a safe procedure with similar outcomes to left HALDN.
本回顾性研究旨在分析在腹腔镜辅助供体肾切术(HAND)中,供体肾脏的位置是否会影响供体和受者的术后结果。纳入了 2006 年 1 月至 2018 年 1 月期间在英国一家大型三级移植中心接受 HAND 的 739 名供体。比较了左右 HAND 中供体的转化率、发病率、热缺血和冷缺血时间以及受者失败率、血管和输尿管并发症。604 例(81.7%)接受了左侧 HAND,135 例(18.3%)接受了右侧 HAND,平均年龄分别为 47.1 岁和 46.8 岁,性别分布相似。左侧手术时间较短(p=0.003),并且在研究期间左侧手术时间有所缩短,但右侧没有。接受左侧肾脏的受者中,早期技术失败的发生率更高(8 例比 1 例),尽管无统计学意义。大多数中心更喜欢进行左侧肾切除术,而受者外科医生更喜欢将左侧肾脏用于移植,主要是因为左侧静脉较长。这项大型研究为右侧 HAND 肾切除术是一种安全的手术,与左侧 HAND 具有相似的结果提供了保证。