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活体肾移植供体肾切除术后的急性肾损伤及肾功能代偿

Acute kidney injury and the compensation of kidney function after nephrectomy in living donation.

作者信息

Okumura Kenji, Grace Holly, Sogawa Hiroshi, Yamanaga Shigeyoshi

机构信息

Department of Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY 10595, United States.

Department of Surgery, New York Medical College, Valhalla, NY 10595, United States.

出版信息

World J Transplant. 2022 Aug 18;12(8):223-230. doi: 10.5500/wjt.v12.i8.223.

Abstract

Acute kidney injury (AKI) incidence is growing rapidly, and AKI is one of the predictors of inpatient mortality. After nephrectomy, all the patients have decreased kidney function with AKI and recover from AKI. However, the characteristic and behavior of AKI is different from usual AKI and compensatory kidney function has been well known in the postoperative setting, especially in living donors. In this review, we have focused on the compensation of kidney function after nephrectomy in living donors. We discuss factors that have been identified as being associated with kidney recovery in donors including age, sex, body mass index, remnant kidney volume, estimated glomerular filtration rate, and various comorbidities.

摘要

急性肾损伤(AKI)的发病率正在迅速上升,且AKI是住院患者死亡率的预测因素之一。肾切除术后,所有患者的肾功能都会因AKI而下降,并从AKI中恢复。然而,AKI的特征和表现与通常的AKI不同,且在术后环境中,尤其是在活体供肾者中,代偿肾功能已广为人知。在本综述中,我们重点关注了活体供肾者肾切除术后的肾功能代偿情况。我们讨论了已被确定与供肾者肾脏恢复相关的因素,包括年龄、性别、体重指数、残余肾体积、估计肾小球滤过率以及各种合并症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96c/9453297/d51337ecc94c/WJT-12-223-g001.jpg

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