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泌尿科住院患者的死亡率、再入院率和住院时间存在不必要的医院间差异:优先确定质量目标的重要触发因素。

Unwarranted Between-hospital Variation in Mortality, Readmission, and Length of Stay of Urological Admissions: An Important Trigger for Prioritising Quality Targets.

机构信息

Leuven Institute for Healthcare Policy, KU Leuven - University of Leuven, Leuven, Belgium.

Leuven Institute for Healthcare Policy, KU Leuven - University of Leuven, Leuven, Belgium.

出版信息

Eur Urol Focus. 2022 Sep;8(5):1531-1540. doi: 10.1016/j.euf.2021.11.001. Epub 2021 Nov 26.

Abstract

BACKGROUND

Unwarranted between-hospital variation is a persistent health care quality issue. It is unknown whether urology patients are prone to this variation.

OBJECTIVE

To examine between-hospital variation in mortality, readmission, and length of stay for all 22 urological All Patient Refined Diagnosis Related Groups (APR-DRGs).

DESIGN, SETTING, AND PARTICIPANTS: This study included administrative data from 320640 urological admissions in 99 (98%) Belgian acute-care hospitals between 2016 and 2018.

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS

We used hierarchical mixed-effect logistic regression models to estimate hospital-specific and APR-DRG-specific risk-standardised rates for in-hospital mortality, 30-d readmission, and length of stay above the APR-DRG-specific 90th percentile. Between-hospital variation was assessed based on the estimated variance components. Associations of outcomes with patient and hospital characteristics and time trends were examined.

RESULTS AND LIMITATIONS

Our analysis revealed important between-hospital variation in mortality, readmission, and length of stay for urological pathologies, particularly for medical diagnoses. Significant variation was shown in all three outcomes for kidney and urinary tract infections; other kidney and urinary tract diagnoses, signs, and symptoms; urinary stones and acquired upper urinary tract obstruction; and kidney and urinary tract procedures for nonmalignancy. Lowering of mortality rates in upper-quartile hospitals to the median could potentially save 41.5% of deaths in these hospitals, with the largest absolute gain for kidney and urinary tract infections and kidney and urinary tract malignancy. Limitations included a likely underestimation of readmission rates.

CONCLUSIONS

Urological patient outcomes are characterised by unwarranted between-hospital variation. We recommend improvement initiatives to prioritise kidney and urinary tract infections because of significant variation across the three outcomes and the largest potential gain in lives saved.

PATIENT SUMMARY

We found notable between-hospital variation in mortality, readmission, and length of stay for urological hospital admissions in Belgium. As much as 41.5% of deaths could potentially be avoided if underperforming hospitals improved. Targeting kidney and urinary tract infections could help reduce variation.

摘要

背景

医院间不必要的差异是持续存在的医疗质量问题。目前尚不清楚泌尿科患者是否容易出现这种差异。

目的

检查所有 22 个泌尿科全患者细化诊断相关组 (APR-DRGs) 的死亡率、再入院率和住院时间的医院间差异。

设计、设置和参与者:本研究纳入了 2016 年至 2018 年期间在比利时 99 家(98%)急性护理医院的 320640 名泌尿科住院患者的行政数据。

结果测量和统计分析

我们使用分层混合效应逻辑回归模型,估计医院特异性和 APR-DRG 特异性风险标准化死亡率、30 天再入院率和住院时间超过 APR-DRG 特异性第 90 百分位数的比率。基于估计的方差分量评估医院间差异。检查了结果与患者和医院特征以及时间趋势的关联。

结果和局限性

我们的分析显示,泌尿科疾病的死亡率、再入院率和住院时间存在重要的医院间差异,特别是对于医疗诊断。在所有三种结果中,肾脏和尿路感染、其他肾脏和尿路感染诊断、体征和症状、尿路结石和获得性上尿路梗阻以及非恶性肿瘤的肾脏和尿路手术都显示出显著的差异。将高四分位医院的死亡率降低到中位数可能会使这些医院的 41.5%的死亡人数得到挽救,而肾脏和尿路感染以及肾脏和尿路恶性肿瘤的绝对获益最大。局限性包括再入院率的可能低估。

结论

泌尿科患者的结局存在不必要的医院间差异。我们建议采取改进措施,将重点放在肾脏和尿路感染上,因为这三个结果存在显著差异,并且在挽救生命方面的潜在获益最大。

患者总结

我们发现比利时泌尿科住院患者的死亡率、再入院率和住院时间存在显著的医院间差异。如果表现不佳的医院能够改善,多达 41.5%的死亡病例可能可以避免。针对肾脏和尿路感染可能有助于减少差异。

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