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偏头痛现状:现有和新兴疗法的更新。

The state of migraine: An update on current and emerging treatments.

机构信息

MBBS, FRACP, Consultant Neurologist, Department of Neurology, Alfred Hospital and Monash University, Melbourne, Vic; Consultant Neurologist, Department of Neurology, Austin Health, Heidelberg, Vic.

MBBS (Hons), FRACGP, General Practitioner, Rowville Health, Rowville, Vic.

出版信息

Aust J Gen Pract. 2021 Dec;50(12):915-921. doi: 10.31128/AJGP-01-21-5807.

Abstract

BACKGROUND

Migraine is a common neurological disorder, affecting one in seven people, and is the second leading cause of disability worldwide.

OBJECTIVE

The aim of this article is to summarise the diagnosis, pathophysiology and treatment of migraine.

DISCUSSION

Key to limiting the disability of migraine and progression to chronic migraine is addressing modifiable risk factors, including implementing effective preventive treatment and avoiding overuse of acute treatment. In this article, the authors review strategies for effective acute and preventive treatment of migraine and introduce the new treatments of migraine targeting calcitonin gene-related peptide signalling.

摘要

背景

偏头痛是一种常见的神经系统疾病,影响七分之一的人,是全球第二大致残原因。

目的

本文旨在总结偏头痛的诊断、病理生理学和治疗。

讨论

限制偏头痛残疾和向慢性偏头痛进展的关键是解决可改变的危险因素,包括实施有效的预防治疗和避免过度使用急性治疗。在本文中,作者回顾了偏头痛有效急性和预防治疗的策略,并介绍了针对降钙素基因相关肽信号的偏头痛新治疗方法。

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