Ohl Nadine, Zingel Rebecca, Kostev Karel
Int J Clin Pharmacol Ther. 2022 Feb;60(2):79-86. doi: 10.5414/CP204098.
The aim of this study was to investigate the representativeness of the German IQVIA Vaccine Analyzer (VA) database with respect to vaccination rates in Germany.
Descriptive statistics for the demographic characteristics of the patients like gender and age distribution and vaccination rates of various types of vaccinations in children, adolescents, and adults were calculated and compared to official data sources in Germany. The vaccination rates were calculated as the ratio between extrapolated vaccinated patient numbers from the database and official population counts from the Federal Statistical Office.
The sex distribution for patients attending general practitioners (GPs) and those attending pediatricians was similar to the German population. The age distribution of the adult German population was comparable to that of the GP and gynecologist patients included in our study. There was good agreement between vaccination rates for diphtheria, tetanus, pertussis, and poliomyelitis in this study (79%) and the rates for the general population according to official sources (78%). HPV vaccination rates in boys in 2018/2019 (1.9%) were also close to the German national rate of 1.3% of all boys reported at the end of 2018. This study found slightly higher vaccination rates for influenza in adults aged over 60 (46%) than the national rate (39%).
The study indicates good accordance between the VA and official reference data for different vaccination rates, especially for children, and indicates that the VA database is suitable for epidemiological studies on vaccines.
本研究旨在调查德国IQVIA疫苗分析仪(VA)数据库在德国疫苗接种率方面的代表性。
计算了患者人口统计学特征(如性别和年龄分布)以及儿童、青少年和成人各类疫苗接种率的描述性统计数据,并与德国官方数据源进行比较。疫苗接种率通过数据库中推断的接种患者数量与联邦统计局的官方人口计数之比来计算。
看全科医生(GP)的患者和看儿科医生的患者的性别分布与德国人口相似。德国成年人口的年龄分布与我们研究中纳入的全科医生和妇科医生患者的年龄分布相当。本研究中白喉、破伤风、百日咳和脊髓灰质炎的疫苗接种率(79%)与官方来源的普通人群接种率(78%)之间有良好的一致性。2018/2019年男孩的人乳头瘤病毒(HPV)疫苗接种率(1.9%)也接近2018年底报告的德国所有男孩1.3%的全国接种率。本研究发现60岁以上成年人的流感疫苗接种率(46%)略高于全国接种率(39%)。
该研究表明VA数据库与官方参考数据在不同疫苗接种率方面,尤其是儿童疫苗接种率方面具有良好的一致性,表明VA数据库适用于疫苗的流行病学研究。