Weill Cornell Medicine Medical College, United States of America.
Department of Radiology, NewYork-Presbyterian Hospital/Weill Cornell Medicine, United States of America.
Clin Imaging. 2022 Feb;82:161-165. doi: 10.1016/j.clinimag.2021.11.007. Epub 2021 Nov 20.
Cerebral Amyloid Angiopathy (CAA) is a cerebrovascular disease prevalent in elderly patients and strongly associated with cognitive decline and intracranial hemorrhage. Inflammatory forms of CAA (CAA-Related Inflammation i.e. CAA-ri and Amyloid-Beta Related Angiitis i.e. ABRA) are responsible for rapid neurocognitive decline, but are highly responsive to corticosteroid treatment. We present a patient with history of CAA who developed probable CAA-ri/ABRA three months after an acute ischemic stroke. We review the literature and imaging criteria for CAA-ri/ABRA, and propose further research for any association between these entities and blood-brain barrier disruption in the setting of ischemia.
脑淀粉样血管病（Cerebral Amyloid Angiopathy，CAA）是一种常见于老年患者的脑血管疾病，与认知能力下降和颅内出血密切相关。CAA 的炎症形式（即 CAA-相关炎症，CAA-Related Inflammation，CAA-ri 和 β淀粉样蛋白相关血管炎，Amyloid-Beta Related Angiitis，ABRA）是导致快速神经认知能力下降的原因，但对皮质类固醇治疗反应良好。我们介绍了一位有 CAA 病史的患者，他在急性缺血性中风后三个月出现了可能的 CAA-ri/ABRA。我们回顾了 CAA-ri/ABRA 的文献和影像学标准，并提出了进一步的研究，以探讨这些实体与缺血状态下血脑屏障破坏之间的任何关联。
