Department of Neurology, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha, 410008, Hunan Province, China.
BMC Neurol. 2021 Nov 30;21(1):465. doi: 10.1186/s12883-021-02497-x.
Spinal subarachnoid haemorrhage is extremely rare in cases of subarachnoid haemorrhage and possesses servere characteristics. Additionally, spinal rheumatoid vasculitis is rare for spinal subarachnoid haemorrhage. The pathogenesis is unknown.
A 52-year-old woman with a 10-year history of seropositive rheumatoid arthritis was managed with leflunomide and celecoxib, and stable low disease activity was achieved. The patient had also been diagnosed with spinal subarachnoid haemorrhage secondary to isolated spinal rheumatoid vasculitis and obtained good therapeutic effects.
This is the first case to describe spinal subarachnoid haemorrhage secondary to isolated spinal vasculitis in a patient with rheumatoid arthritis, which provides more proof of anomalous neovascularization in the central nervous system in rheumatoid arthritis.
蛛网膜下腔出血在蛛网膜下腔出血的情况下极为罕见,且具有严重特征。此外,脊柱类风湿性血管炎在蛛网膜下腔出血中也较为罕见。其发病机制尚不清楚。
一名 52 岁女性,有 10 年血清阳性类风湿关节炎病史,采用来氟米特和塞来昔布治疗,病情稳定且处于低活动度。该患者还被诊断为孤立性脊柱类风湿性血管炎导致的脊髓蛛网膜下腔出血,并获得了良好的治疗效果。
这是首例描述类风湿关节炎患者孤立性脊柱血管炎导致脊髓蛛网膜下腔出血的病例,为类风湿关节炎中枢神经系统异常新生血管化提供了更多证据。