类风湿性血管炎：类风湿关节炎的早期表现。
Rheumatoid vasculitis: early presentation of rheumatoid arthritis.
作者信息
Abdulqader Yasir, Al-Ani Muhsen, Parperis Konstantinos
机构信息
Department of Internal Medicine, Maricopa Integrated Health System, Phoenix, Arizona, USA.
Maricopa Medical Center, Phoenix, Arizona, USA.
出版信息
BMJ Case Rep. 2016 Nov 8;2016:bcr2016217557. doi: 10.1136/bcr-2016-217557.
Abstract
Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis and may affect small-to-medium-sized vessels. Here, we report a case of a 49-year-old man who presented with amaurosis fugax in the left eye, symmetric polyarthritis, Raynaud's symptoms and paraesthesia in both lower extremities. The patient subsequently experienced right foot drop, nail fold infracts and gangrene of his right second toe. He was found to have a high titre of rheumatoid factor and treatment with rituximab and high dose of corticosteroids led to significant improvement of his symptoms. This is rare case describing the early onset of rheumatoid vasculitis in a patient with rheumatoid arthritis.
摘要
类风湿性血管炎是类风湿性关节炎一种罕见的晚期并发症，可能会影响中小血管。在此，我们报告一例49岁男性患者，其出现左眼一过性黑矇、对称性多关节炎、雷诺氏症状以及双下肢感觉异常。该患者随后出现右脚下垂、甲襞梗死以及右足第二趾坏疽。发现他类风湿因子滴度高，使用利妥昔单抗和高剂量皮质类固醇治疗后其症状有显著改善。这是一例描述类风湿性关节炎患者类风湿性血管炎早期发病的罕见病例。
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