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股骨倾斜角和 T1 骨盆角在预测成人脊柱畸形脊柱手术后生活质量中的作用。

The role of femoral obliquity angle and T1 pelvic angle in predicting quality of life after spinal surgery in adult spinal deformities.

机构信息

Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Largo A. Gemelli, 8, 00168, Rome, Italy.

Istituto di Ortopedia e Traumatologia, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

BMC Musculoskelet Disord. 2021 Nov 30;22(Suppl 2):999. doi: 10.1186/s12891-021-04823-3.

Abstract

BACKGROUND

Adult spinal deformities (ASD) represent a growing clinical condition related to chronic pain, disability and reduction in quality of life (QoL). A strong correlation among spinal alignment, spinopelvic parameters and QoL after spinal fusion surgery in ASD patients was thoroughly investigated over the last decade, However, only few studies focused on the relationship between lumbo-pelvic-femoral parameters - such as Femoral Obliquity Angle (FOA), T1 Pelvic Angle (TPA) and QoL.

METHODS

Radiological and clinical data from 43 patients surgically treated with thoracolumbar posterior spinal fusion for ASD between 2015 and 2018 were retrospectively analyzed. The primary outcomes were the correlation between preoperative spino-pelvic-femoral parameters and postoperative clinical, functional outcomes and QoL. Secondary outcomes were: changes in sagittal radiographic parameters spino-pelvic-femoral, clinical and functional outcomes and the rate of complications after surgery.

RESULTS

Using Spearman's rank correlation coefficients, spinopelvic femoral parameters (FOA, TPA, pre and post-operative) are directly statistically correlated to the quality of life (ODI, SRS-22, pre and post-operative; > 0,6 strong correlation, p <  0.05). Stratifying the patients according pre preoperative FOA value (High FOA ≥ 10 and Normal/Low FOA <  10), those belonging to the first group showed worse clinical (VAS: 5.2 +/- 1.4 vs 2.9 +/- 0.8) and functional outcomes (ODI: 35.6+/- 6.8 vs 23.2 +/- 6.5) after 2 years of follow-up and a greater number of mechanical complications (57.9% vs 8.3% p <  0.0021).

CONCLUSION

Based on our results, preoperative FOA and TPA could be important prognostic parameters for predicting disability and quality of life after spinal surgery in ASD patients and early indicators of possible spinal sagittal malalignment. FOA and TPA, like other and better known spinopelvic parameters, should always be considered when planning corrective surgery in ASD patients.

摘要

背景

成人脊柱畸形(ASD)是一种与慢性疼痛、残疾和生活质量(QoL)降低相关的日益严重的临床病症。在过去十年中,人们深入研究了 ASD 患者脊柱融合手术后脊柱排列、骨盆参数与 QoL 之间的强烈相关性,但只有少数研究关注腰椎骨盆股骨参数(如股骨倾斜角(FOA)、T1 骨盆角(TPA)与 QoL)之间的关系。

方法

回顾性分析了 2015 年至 2018 年间接受胸腰椎后路脊柱融合术治疗 ASD 的 43 例患者的影像学和临床资料。主要结果是术前脊柱骨盆股骨参数与术后临床、功能结果和 QoL 的相关性。次要结果是:脊柱骨盆股骨影像学参数、临床和功能结果的变化,以及术后并发症的发生率。

结果

使用 Spearman 秩相关系数,脊柱骨盆股骨参数(FOA、TPA、术前和术后)与生活质量(ODI、SRS-22、术前和术后;>0.6 为强相关,p<0.05)呈直接统计学相关性。根据术前 FOA 值(高 FOA≥10 和正常/低 FOA<10)对患者进行分层,属于第一组的患者在 2 年随访后表现出更差的临床(VAS:5.2 +/-1.4 与 2.9 +/-0.8)和功能结果(ODI:35.6+/-6.8 与 23.2 +/-6.5),并且机械并发症的发生率更高(57.9%与 8.3%,p<0.0021)。

结论

基于我们的结果,术前 FOA 和 TPA 可能是预测 ASD 患者脊柱手术后残疾和生活质量的重要预后参数,也是脊柱矢状面失平衡的早期指标。在计划 ASD 患者的矫正手术时,应始终考虑 FOA 和 TPA 等其他更为人熟知的脊柱骨盆参数。

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