Smith K P, Zardiackas L D, Didlake R H
J Surg Res. 1986 Feb;40(2):120-5. doi: 10.1016/0022-4804(86)90112-5.
Traditional methods of measuring wound strength have often ignored one of the most important variables, i.e., wound surface area. Using a readily reproducible method of determining wound surface area, the effect of topical vitamin A on steroid-treated rats was studied. Findings revealed a significant (P less than 0.001) increase in wound strength with topical vitamin A application. No difference could be detected between steroid-treated and saline-treated rats when wound surface area was taken into account. Measurement of wound surface area is essential for meaningful results in wound healing studies.
传统的测量伤口强度的方法常常忽略了一个最重要的变量，即伤口表面积。采用一种易于重复的测定伤口表面积的方法，研究了局部应用维生素A对类固醇处理大鼠的影响。研究结果显示，局部应用维生素A可使伤口强度显著增加（P小于0.001）。当考虑伤口表面积时，类固醇处理组和生理盐水处理组的大鼠之间未检测到差异。在伤口愈合研究中，测量伤口表面积对于获得有意义的结果至关重要。
