Katsimpris P, Tripsianis G, Printza A, Giotakis E, Simopoulos E, Constantinidis J, Katotomichelakis M
Department of Otorhinolaryngology, Democritus University of Thrace, Alexandroupolis, Greece.
Department of Statistics, Democritus University of Thrace, Alexandroupolis, Greece.
J Laryngol Otol. 2022 Apr;136(4):341-348. doi: 10.1017/S0022215121004011. Epub 2021 Dec 1.
This study aimed to develop the Greek versions of the Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire for adult and pediatric populations, discuss their differences and detect the impact of age and gender on quality of life questionnaire results.
Ninety-eight patients with allergic rhinitis participated. Quality of Life evaluation was made by two generic (Short Form-36 and Beck Depression Inventory) and two disease-specific questionnaires (Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire). Symptom evaluation was made by the Total 5 Symptoms Score assessment.
Internal consistency and test-retest reliability of both questionnaires was high. Convergent validity showed statistically significant negative correlations of total Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire with overall Short Form-36 Health Survey score and positive correlations with Beck Depression Inventory and Total 5 Symptoms Score. Discriminative validity demonstrated statistically significant improvement for all instruments and all domains after treatment. Females presented highly significant increased scores. Patient age was positively correlated with total scores of Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire. The clinically significant improvement after treatment was higher among females than males, while it was independent of patient age.
Rhinoconjunctivitis Quality of Life Questionnaire and Mini-Rhinoconjunctivitis Quality of Life Questionnaire proved to be valid and reliable methods of assessment of allergic rhinitis-related quality of life in children, adolescents and adults.
本研究旨在开发适用于成人和儿童群体的希腊语版变应性鼻炎生活质量问卷及迷你变应性鼻炎生活质量问卷，探讨两者差异，并检测年龄和性别对生活质量问卷结果的影响。
98例变应性鼻炎患者参与研究。采用两份通用问卷（简明健康状况调查量表和贝克抑郁量表）及两份疾病特异性问卷（变应性鼻炎生活质量问卷和迷你变应性鼻炎生活质量问卷）进行生活质量评估。通过5项症状总分评估进行症状评价。
两份问卷的内部一致性和重测信度均较高。聚合效度显示，变应性鼻炎生活质量问卷总分及迷你变应性鼻炎生活质量问卷总分与简明健康状况调查量表总体得分呈显著负相关，与贝克抑郁量表及5项症状总分呈正相关。区分效度表明，治疗后所有工具及所有领域均有统计学显著改善。女性得分显著升高。患者年龄与变应性鼻炎生活质量问卷总分及迷你变应性鼻炎生活质量问卷总分呈正相关。治疗后临床上的显著改善女性高于男性，且与患者年龄无关。
变应性鼻炎生活质量问卷和迷你变应性鼻炎生活质量问卷被证明是评估儿童、青少年和成人变应性鼻炎相关生活质量的有效且可靠的方法。
