Valero A, Alonso J, Antépara I, Baró E, Colás C, del Cuvillo A, Ferrer M, Herdman M, Marti-Guadaño E, Monclús L, Navarro-Pulido A M, Sastre J, Izquierdo I, Mullol J
Unidad de Alergia, Servicio de Neumologia y Alergia Respiratoria, Hospital Clinic, Barcelona, Spain.
Allergy. 2007 Dec;62(12):1372-8. doi: 10.1111/j.1398-9995.2007.01552.x.
We compared the psychometric properties of the ESPRINT-15, the short form of a new Spanish instrument to measure health-related quality of life in allergic rhinitis (AR) patients, with those of the Mini-Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ).
The questionnaires were compared in Spanish patients with intermittent allergic rhinitis (IAR) or persistent AR in a prospective, observational study. Floor and ceiling effects, internal consistency (Cronbach's alpha), test-retest reliability (intraclass correlation coefficient; ICC), convergent and known groups validity, and sensitivity to change (standardized response means; SRMs) were compared.
In terms of content, while the MiniRQLQ has a dimension covering practical problems and places more emphasis on symptoms, the ESPRINT-15 has two dimensions (Sleep and Psychological impact) which are not included in the MiniRQLQ. In the validation study, 400 patients were included and 59% of the sample had persistent AR. There were no significant floor or ceiling effects on any dimension on either questionnaire. Cronbach's alpha values for the ESPRINT-15 and MiniRQLQ overall scores were 0.92 and 0.90, respectively. In 48 clinically stable patients, ICCs were 0.80 and 0.77, respectively. Both instruments discriminated between patients with IAR and persistent AR. Correlations with symptom scores and generic measures were moderate to strong. SRMs for overall scores and individual dimensions on the two questionnaires in the 197 patients reporting a change in health status ranged from 0.7 to 1.3.
Both questionnaires performed well in psychometric terms. The ESPRINT-15 is particularly recommended for use in Spanish-speaking populations.
我们比较了ESPRINT - 15（一种用于测量过敏性鼻炎（AR）患者健康相关生活质量的新西班牙文简版工具）与迷你鼻结膜炎生活质量问卷（MiniRQLQ）的心理测量特性。
在一项前瞻性观察研究中，对西班牙患有间歇性过敏性鼻炎（IAR）或持续性AR的患者的问卷进行了比较。比较了地板效应和天花板效应、内部一致性（克朗巴哈系数）、重测信度（组内相关系数；ICC）、收敛效度和已知组效度以及对变化的敏感性（标准化反应均值；SRM）。
在内容方面，虽然MiniRQLQ有一个涵盖实际问题的维度且更强调症状，但ESPRINT - 15有两个维度（睡眠和心理影响）未包含在MiniRQLQ中。在验证研究中，纳入了400名患者，样本中59%患有持续性AR。两份问卷在任何维度上均未出现显著的地板效应或天花板效应。ESPRINT - 15和MiniRQLQ总分的克朗巴哈系数分别为0.92和0.90。在48名临床稳定的患者中，ICC分别为0.80和0.77。两种工具都能区分IAR患者和持续性AR患者。与症状评分和通用测量指标的相关性为中度至高度。在197名报告健康状况有变化的患者中，两份问卷总分和各维度的SRM范围为0.7至1.3。
两份问卷在心理测量方面表现良好。特别推荐ESPRINT - 15用于说西班牙语的人群。
