Wong Ting-Hway, Tan Timothy Xin Zhong, Malhotra Rahul, Nadkarni Nivedita V, Chua Wei Chong, Loo Lynette Ma, Iau Philip Tsau Choong, Ang Arron Seng Hock, Goo Jerry Tiong Thye, Chan Kim Chai, Matchar David Bruce, Seow Dennis Chuen Chai, Nguyen Hai V, Ng Yee Sien, Chan Angelique, Fook-Chong Stephanie, Tang Tjun Yip, Ong Marcus Eng Hock
Health Services and Systems Research, Duke-NUS Graduate Medical School, Singapore; Department of General Surgery, Singapore General Hospital, Singapore.
Department of Emergency Medicine, Singapore General Hospital, Singapore.
J Am Med Dir Assoc. 2022 Apr;23(4):646-653.e1. doi: 10.1016/j.jamda.2021.10.016. Epub 2021 Nov 27.
Frailty is associated with morbidity and mortality in older injured patients. However, for older blunt-trauma patients, increased frailty may not manifest in longer length of stay at index admission. We hypothesized that owing to time spent in hospital from readmissions, frailty would be associated with less total time at home in the 1-year postinjury period.
Prospective, nationwide, multicenter cohort study.
All Singaporean residents aged ≥55 years admitted for blunt trauma with an Injury Severity Score (ISS) or New Injury Severity Score (NISS) ≥10 from March 2016 to July 2018.
Frailty (by modified Fried criteria) was assessed at index admission, based on questions on preinjury weight loss, slowness, exhaustion, physical activity, and grip strength at the time of recruitment. Low time at home was defined as >14 hospitalized days within 1 year postinjury. The contribution of planned and unplanned readmission to time at home postinjury was explored. Functional trajectory (by Barthel Index) over 1 year was compared by frailty.
Of the 218 patients recruited, 125 (57.3%) were male, median age was 72 years, and 48 (22.0%) were frail. On univariate analysis, frailty [relative to nonfrail: odds ratio (OR) 3.45, 95% confidence interval (CI) 1.33-8.97, P = .01] was associated with low time at home. On multivariable analysis, after inclusion of age, gender, ISS, intensive care unit admission, and surgery at index admission, frailty (OR 5.21, 95% CI 1.77-15.34, P < .01) remained significantly associated with low time at home in the 1-year postinjury period. Unplanned readmissions were the main reason for frail participants having low time at home. Frail participants had poorer function in the 1-year postinjury period.
In the year following blunt trauma, frail older patients experience lower time at home compared to patients who were not frail at baseline. Screening for frailty should be considered in all older blunt-trauma patients, with a view to being prioritized for postdischarge support.
衰弱与老年创伤患者的发病率和死亡率相关。然而,对于老年钝性创伤患者,衰弱程度增加可能不会表现为初次入院时住院时间延长。我们假设,由于再次入院导致的住院时间,衰弱与受伤后1年内在家总时间减少有关。
前瞻性、全国性、多中心队列研究。
2016年3月至2018年7月期间,所有年龄≥55岁、因钝性创伤入院且损伤严重程度评分(ISS)或新损伤严重程度评分(NISS)≥10的新加坡居民。
在初次入院时根据招募时关于受伤前体重减轻、行动迟缓、疲惫、身体活动和握力的问题评估衰弱情况(采用改良的Fried标准)。在家时间少定义为受伤后1年内住院天数>14天。探讨计划内和计划外再次入院对受伤后在家时间的影响。按衰弱情况比较1年内的功能轨迹(采用Barthel指数)。
在招募的218例患者中,125例(57.3%)为男性,中位年龄为72岁,48例(22.0%)衰弱。单因素分析显示,衰弱[相对于非衰弱:比值比(OR)3.45,95%置信区间(CI)1.33 - 8.97,P = 0.01]与在家时间少相关。多变量分析显示,纳入年龄、性别、ISS、入住重症监护病房和初次入院时的手术情况后,衰弱(OR 5.21,95% CI 1.77 - 15.34,P < 0.01)在受伤后1年内仍与在家时间少显著相关。计划外再次入院是衰弱参与者在家时间少的主要原因。衰弱参与者在受伤后1年内功能较差。
在钝性创伤后的一年中,衰弱的老年患者与基线时不衰弱的患者相比,在家时间更少。应考虑对所有老年钝性创伤患者进行衰弱筛查,以便在出院后获得优先支持。