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酒渣鼻内的基底细胞癌:巧合还是有关联?

Basal cell carcinoma within rhinophyma: coincidence or relationship?

作者信息

Chlebicka Iwona, Stefaniak Aleksandra A, Bieniek Andrzej, Matusiak Łukasz, Woźniak Zdzisław, Szepietowski Jacek C

机构信息

Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland.

Department of Pathology, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Postepy Dermatol Alergol. 2021 Oct;38(5):855-857. doi: 10.5114/ada.2020.99367. Epub 2020 Oct 13.

Abstract

INTRODUCTION

Rhinophyma is a relatively rare form of rosacea, while basal cell carcinoma (BCC) is the most frequent skin cancer in humans - both diseases prevail in the elderly.

AIM

To analyse patients with rhinophyma treated surgically in the Dermatosurgery Unit and look for possible cases with BCC within the rhinophyma.

MATERIAL AND METHODS

We performed a retrospective review of all treated rhinophymas in the Dermatosurgery Unit in 2004-2019.

RESULTS

Among 140 rhinophyma patients 2 (1.4%) subjects with concomitant clinically diagnosed and histologically confirmed BCC were found, with BCC located in the hypertrophic tissue of the nose. There were no patients with BCC located in other anatomical regions of the skin. Both of these patients were in more advanced age.

CONCLUSIONS

Taking into consideration these two conditions: advanced age and anatomical location, typical for BCC, one may speculate that the development of BCC within rhinophyma is rather a simple coincidence. However, more numerous series of patients with rhinophyma are needed to clear the controversy of BCC within rhinophyma hypertrophic tissue.

摘要

引言

鼻赘是酒渣鼻的一种相对罕见的形式,而基底细胞癌(BCC)是人类最常见的皮肤癌——这两种疾病在老年人中更为普遍。

目的

分析在皮肤外科接受手术治疗的鼻赘患者,并在鼻赘患者中寻找可能合并基底细胞癌的病例。

材料与方法

我们对2004年至2019年在皮肤外科接受治疗的所有鼻赘患者进行了回顾性研究。

结果

在140例鼻赘患者中,发现2例(1.4%)同时患有临床诊断并经组织学证实的基底细胞癌,基底细胞癌位于鼻部肥厚组织中。没有患者的基底细胞癌位于皮肤的其他解剖区域。这两名患者年龄都较大。

结论

考虑到基底细胞癌的两个典型情况:年龄较大和解剖位置,有人可能推测鼻赘内基底细胞癌的发生相当于是一种简单的巧合。然而,需要更多鼻赘患者系列研究来消除鼻赘肥厚组织内基底细胞癌的争议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1450/8610061/bf1256634539/PDIA-38-41898-g001.jpg

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