酒渣鼻并发多灶性基底细胞癌：病例报告及文献复习
Multiple Foci of Basal Cell Carcinoma Arising in Rhinophyma: A Case Report and Literature Review.
作者信息
Faenza Mario, Molle Marcello, Ronchi Andrea, Pagliuca Francesca, Pelella Tommaso, Nicoletti Maria Maddalena, Crisci Erminia, Pieretti Gorizio, Ferraro Giuseppe Andrea
机构信息
Plastic Surgery Unit, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania "Luigi Vanvitelli," Naples, Italy.
Pathology Unit, Mental and Physical Health and Preventive Medicine Department, University of Campania "Luigi Vanvitelli," Naples, Italy.
出版信息
JPRAS Open. 2023 Oct 5;38:186-192. doi: 10.1016/j.jpra.2023.10.001. eCollection 2023 Dec.
BACKGROUND
Rhinophyma is a benign condition caused by the excessive growth of sebaceous glands in the nasal tissue, presenting with symptoms such as nasal hypertrophy, erythema, and papules. Cases of basal cell carcinoma in rhinophyma have been reported in literature, but its etiological role remains unclear. It is uncertain whether rhinophyma is predisposed to neoplasm development or if their coexistence is coincidental.
MATERIAL AND METHOD
We conducted a literature survey to identify such cases reported over the years.
RESULTS
We identified 22 studies reporting a total of 47 cases in the literature, all involving male patients. The most common pattern of occurrence was the rapid growth of a nodular formation within the context of rhinophyma.
DISCUSSIONS AND CONCLUSION
The elucidation of the association between basal cell carcinoma and rhinophyma remains challenging. The presence of multiple foci supports the theory that rhinophyma may play a role in their development, but larger studies are needed to establish a causal relationship.
背景
鼻赘是一种由鼻腔组织中皮脂腺过度生长引起的良性病症，表现为鼻肥大、红斑和丘疹等症状。文献中已报道了鼻赘合并基底细胞癌的病例，但其病因学作用仍不明确。尚不确定鼻赘是否易发生肿瘤，或者它们的共存是否只是巧合。
材料与方法
我们进行了文献调查，以确定多年来报道的此类病例。
结果
我们在文献中确定了22项研究，共报告了47例病例，所有病例均为男性患者。最常见的发生模式是在鼻赘的背景下结节形成迅速生长。
讨论与结论
阐明基底细胞癌与鼻赘之间的关联仍然具有挑战性。多个病灶的存在支持了鼻赘可能在其发展中起作用的理论，但需要更大规模的研究来建立因果关系。
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