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基底细胞癌:关于这种最常见的人类癌症能有哪些新认识?一项对单中心180例病例的横断面前瞻性研究。

Basal cell carcinoma: what new can be learned about the most common human cancer? A cross-sectional prospective study of 180 cases in a single centre.

作者信息

Chlebicka Iwona, Stefaniak Aleksandra, Matusiak Łukasz, Szepietowski Jacek C

机构信息

Department of Dermatology, Venereology, and Allergology, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Postepy Dermatol Alergol. 2021 Dec;38(6):1086-1091. doi: 10.5114/ada.2021.106026. Epub 2021 Oct 22.

Abstract

INTRODUCTION

Basal cell carcinoma (BCC) is the most common cancer in humans, but the reporting of patients with BCC is still not complete. There are a limited number of analyses in the literature on BCC epidemiology.

AIM

To study the epidemiological as well as clinical aspects of BCC by analysing a single centre's experience in the Lower Silesia region of Poland.

MATERIAL AND METHODS

We investigated 180 patients with BCC treated in the Unit of Dermatosurgery, Department of Dermatology, Venereology, and Allergology of Wroclaw Medical University between September 2017 and December 2019.

RESULTS

The mean age of patients with BCC was 70.5 ±11.9 years. The most frequently diagnosed type of BCC was nodular type, at 72% of all patients. BCC occurred most commonly on the face and neck area, at 132 (73.3%), without a statistical difference between males and females. The vast majority of cancers were located on the nose. There was a personal history of skin cancer in 29% of our patients. In 127 (70.6%) subjects, the diameter of the BCC on the day of excision was less than 2 cm.

CONCLUSIONS

The clinical characteristics of our cohort of BCC patients has some similarities with that reported from central Poland and other European countries. However, we found an increase in the incidence of BCC among females.

摘要

引言

基底细胞癌(BCC)是人类最常见的癌症,但BCC患者的报告仍不完整。关于BCC流行病学的文献分析数量有限。

目的

通过分析波兰下西里西亚地区单一中心的经验,研究BCC的流行病学和临床特征。

材料与方法

我们调查了2017年9月至2019年12月期间在弗罗茨瓦夫医科大学皮肤科、性病科和变态反应科皮肤外科治疗的180例BCC患者。

结果

BCC患者的平均年龄为70.5±11.9岁。最常诊断出的BCC类型是结节型,占所有患者的72%。BCC最常见于面部和颈部区域,有132例(73.3%),男女之间无统计学差异。绝大多数癌症位于鼻子上。29%的患者有皮肤癌个人史。在127例(70.6%)受试者中,切除当天BCC的直径小于2cm。

结论

我们的BCC患者队列的临床特征与波兰中部和其他欧洲国家报告的情况有一些相似之处。然而,我们发现女性BCC的发病率有所增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abe1/8802970/9d39df1c7256/PDIA-38-44030-g001.jpg

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