Shittu Saheed Akinola, Athar Sufia, Shaukat Adila, Alansari Lolwa
Department of Obstetrics and Gynaecology Al Wakra Hospital Hamad Medical Corporation Doha Qatar.
Infectious Disease Unit Division of Medicine Al Wakra Hospital Hamad Medical Corporation Doha Qatar.
Clin Case Rep. 2021 Nov 22;9(11):e05078. doi: 10.1002/ccr3.5078. eCollection 2021 Nov.
Chorioamnionitis is an acute inflammation of the membranes and chorion of the placenta typically due to ascending polymicrobial infection in the setting of membrane rupture. It is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. We present a case of placental infection leading to preterm delivery, severe neonatal sepsis, maternal wound infection, postnatal readmission, and prolonged hospital stay. This virulent infection was caused by multidrug-resistant extended-spectrum beta-lactamase (ESBL)-producing (), which represent a major worldwide threat according to the Centre for Disease Control and Prevention (CDC). It was managed with appropriate antibiotic therapy, patient-centered approach, and multidisciplinary team involvement that led to favourable maternal and neonatal outcome.
绒毛膜羊膜炎是胎盘胎膜和绒毛膜的急性炎症，通常是由于胎膜破裂时上行性多微生物感染所致。它是妊娠常见并发症，与孕产妇、围产期及长期不良结局相关。我们报告一例胎盘感染导致早产、严重新生儿败血症、产妇伤口感染、产后再次入院及住院时间延长的病例。这种严重感染由产超广谱β-内酰胺酶（ESBL）的多重耐药菌引起，根据疾病控制与预防中心（CDC）的数据，这是全球主要威胁。通过适当的抗生素治疗、以患者为中心的方法以及多学科团队参与进行管理，最终母婴结局良好。
