Dolma Kalsang, Summerlin Thanh L, Wongprasert Hansa, Lal Charitharth Vivek, Philips Iii Joseph B, Winter Lindy
Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.
AJP Rep. 2018 Oct;8(4):e277-e279. doi: 10.1055/s-0038-1675336. Epub 2018 Oct 29.
Extended-spectrum -lactamase (ESBL)-producing Enterobacteriaceae represent a major worldwide threat. We present three cases of early onset ESBL sepsis in infants born to families from South and Southeast Asia to inform the practitioner community about this emerging threat. Infants with suspected sepsis, whose mother is from Asia or Southeast Asia, should be suspected of having an infection with an ESBL-producing organism, and practitioners should strongly consider adding a carbapenem to their usual initial antibiotic regimen.
产超广谱β-内酰胺酶(ESBL)的肠杆菌科细菌是全球范围内的主要威胁。我们报告了3例南亚和东南亚家庭出生的婴儿早发性ESBL败血症病例,以让从业者群体了解这一新兴威胁。对于疑似败血症且母亲来自亚洲或东南亚的婴儿,应怀疑感染了产ESBL的生物体,从业者应强烈考虑在其常规初始抗生素治疗方案中添加碳青霉烯类药物。