Amonchaisakda Nuntouchaporn, Leeyaphan Charussri
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
IDCases. 2021 Nov 18;26:e01349. doi: 10.1016/j.idcr.2021.e01349. eCollection 2021.
A single varicella infection usually causes lifelong immunity, so recurrent varicella infection is considered rare. Reactivation of the virus as herpes zoster usually develops after a latent period. Here, we report a case of a 48-year-old immunosuppressed patient who presented with rapid-onset symmetrical bilateral papulovesicular eruptions on both legs 3 weeks after having recurrent varicella infection that had been treated with intravenous acyclovir. Varicella zoster virus (VZV) Ag testing was performed on vesicular lesions. The positive result confirmed that VZV had reactivated. It presented in the form of herpes zoster duplex bilateralis symmetricus. This condition is rare and occurs primarily in immunocompromised female hosts.
单次水痘感染通常会产生终身免疫，因此复发性水痘感染被认为很罕见。病毒重新激活引发带状疱疹通常在潜伏期后出现。在此，我们报告一例48岁免疫抑制患者的病例，该患者在复发性水痘感染经静脉注射阿昔洛韦治疗3周后，双下肢迅速出现对称性双侧丘疹水疱性皮疹。对水疱性皮损进行了水痘带状疱疹病毒（VZV）抗原检测。阳性结果证实VZV已重新激活。它表现为双侧对称性带状疱疹双重感染。这种情况很罕见，主要发生在免疫功能低下的女性宿主中。
