荷兰一家军事医院中与HLA - B27相关的反应性脊柱关节病

HLA-B27 associated reactive spondyloarthropathies in a Dutch military hospital.

作者信息

Lionarons R J, van Zoeren M, Verhagen J N, Lammers H A

出版信息

Ann Rheum Dis. 1986 Feb;45(2):141-3. doi: 10.1136/ard.45.2.141.

DOI:10.1136/ard.45.2.141

PMID:3484936

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001836/

Abstract

Forty-two male patients with reactive spondyloarthropathies in a Dutch military hospital are described with mean age of onset 21.9 years. Peripheral arthritis or sacroiliitis was present in all, eye symptoms in 21 (50%), and genitourinary disease in 15 (35.7%). Evidence of antecedent sexually acquired or enterocolitic infection was found only in three (7.2%). HLA-B27 antigen was detected in 34 (81%) of 42 patients. Additional data suggest that reactive spondyloarthropathies are the most common form of inflammatory arthritis in young men.

摘要

荷兰一家军事医院对42例反应性脊柱关节炎男性患者进行了描述，其平均发病年龄为21.9岁。所有患者均有外周关节炎或骶髂关节炎，21例（50%）有眼部症状，15例（35.7%）有泌尿生殖系统疾病。仅3例（7.2%）发现有先前性传播或肠道感染的证据。42例患者中有34例（81%）检测到HLA - B27抗原。其他数据表明，反应性脊柱关节炎是年轻男性中最常见的炎性关节炎形式。