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脾梗死和肺栓塞作为新型冠状病毒肺炎的罕见表现

Splenic infarction and pulmonary embolism as a rare manifestation of COVID-19.

作者信息

Yildiz Egemen, Satilmis Dilay, Cevik Erdem

机构信息

Department of Emergency Medicine, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

出版信息

Turk J Emerg Med. 2021 Oct 29;21(4):214-216. doi: 10.4103/2452-2473.329627. eCollection 2021 Oct-Dec.

DOI:10.4103/2452-2473.329627
PMID:34849435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8593423/
Abstract

Coronavirus disease 2019 (COVID-19) disease leads to a hypercoagulable state and associated with thrombotic events that can cause mortality and morbidity. Thrombotic events include both venous and arterial thrombosis. In this case report, we present a 68-year-old COVID-19 patient with multisystemic infarction who was admitted to the hospital by splenic infarction and later pulmonary embolism diagnosed during the stay in hospital despite anticoagulant use. It is important for emergency physicians to know that patients who had COVID-19 infection but not confirmed or not tested can visit the emergency department due to complications of COVID-19 infection such as thromboembolic events primarily.

摘要

2019冠状病毒病(COVID-19)会导致高凝状态,并伴有可导致死亡和发病的血栓形成事件。血栓形成事件包括静脉血栓和动脉血栓。在本病例报告中,我们介绍了一名68岁的COVID-19患者,该患者发生多系统梗死,因脾梗死入院,住院期间尽管使用了抗凝剂,但后来仍诊断出肺栓塞。对于急诊医生来说,重要的是要知道,那些感染了COVID-19但未确诊或未检测的患者,可能主要由于COVID-19感染的并发症(如血栓栓塞事件)而前往急诊科就诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/fde12e4ee47e/TJEM-21-214-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/5975d13ecae6/TJEM-21-214-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/fc82fa4786ef/TJEM-21-214-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/fde12e4ee47e/TJEM-21-214-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/5975d13ecae6/TJEM-21-214-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/fc82fa4786ef/TJEM-21-214-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fd3/8593423/fde12e4ee47e/TJEM-21-214-g003.jpg

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本文引用的文献

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Concomitant renal and splenic infarction as a complication of COVID-19: a case report and literature review.新型冠状病毒肺炎并发症:肾脾梗死伴发一例报告及文献复习
Infez Med. 2020 Dec 1;28(4):611-615.
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Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System.在纽约市医疗系统中 COVID-19 住院患者中的血栓形成。
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Multisystemic Infarctions in COVID-19: Focus on the Spleen.新型冠状病毒肺炎中的多系统梗死:聚焦于脾脏
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Thromboinflammation and the hypercoagulability of COVID-19.新冠病毒感染的血栓炎症与高凝状态
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Incidence of thrombotic complications in critically ill ICU patients with COVID-19.COVID-19 重症监护病房危重症患者的血栓并发症发生率。
Thromb Res. 2020 Jul;191:145-147. doi: 10.1016/j.thromres.2020.04.013. Epub 2020 Apr 10.
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Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms.血栓炎症:治疗性靶向凝血和其他宿主防御机制的挑战。
Blood. 2019 Feb 28;133(9):906-918. doi: 10.1182/blood-2018-11-882993. Epub 2019 Jan 14.