Landsman Alexander, Pellegrini James R, Tiwana Muhammad S, Berry Shivankshi, Singh Jaswinder
Internal Medicine, Nassau University Medical Center, East Meadow, USA.
Cureus. 2022 May 11;14(5):e24912. doi: 10.7759/cureus.24912. eCollection 2022 May.
Coronavirus disease 2019 (COVID-19) is known to primarily have respiratory tract involvement, but thromboembolic complications can occur as well, leading to increased overall mortality seen in these patients. We present a case of a patient infected with COVID-19 who then developed two simultaneous thrombotic events. Our patient is a 57-year-old male who presented to the emergency department with sudden onset dysarthria and left lower extremity weakness. Medical records indicated he recently tested positive for COVID-19 infection 10 days ago. Magnetic resonance imaging (MRI) of the brain revealed an acute right cerebellar infarction as well as acute bilateral thalamic infarcts. Later in the hospital course, computed tomography angiography (CTA) of the chest revealed a right lower lobe segmental pulmonary artery embolism. Patients with COVID-19 have been seen to develop a wide spectrum of thromboembolic manifestations, most commonly being venous thromboembolism. Arterial thrombosis and microvascular disease can be detected as well. Early diagnosis and treatment of clotting disease is essential and may decrease overall mortality in COVID-19-infected patients.
2019冠状病毒病（COVID-19）主要累及呼吸道，但也可能出现血栓栓塞并发症，导致这些患者的总体死亡率上升。我们报告一例感染COVID-19的患者，该患者随后同时发生了两起血栓形成事件。我们的患者是一名57岁男性，因突发构音障碍和左下肢无力就诊于急诊科。病历显示他10天前COVID-19感染检测呈阳性。脑部磁共振成像（MRI）显示急性右小脑梗死以及急性双侧丘脑梗死。在住院过程中，胸部计算机断层血管造影（CTA）显示右下叶节段性肺动脉栓塞。已观察到COVID-19患者会出现广泛的血栓栓塞表现，最常见的是静脉血栓栓塞。也可检测到动脉血栓形成和微血管疾病。凝血疾病的早期诊断和治疗至关重要，可能会降低COVID-19感染患者的总体死亡率。
