Nilsson I M, Felding P, Lecander I, Lennér C, Astedt B
Br J Haematol. 1986 Feb;62(2):215-20. doi: 10.1111/j.1365-2141.1986.tb02924.x.
The content of tissue plasminogen activator inhibitor (t-PA-I), and of specific pregnancy plasma-PA-I reacting with antibodies to placental-PA-I, was measured in platelet-poor plasma (PPP), platelet-rich plasma (PRP), serum and platelet lysate, both from pregnant women and healthy non-pregnant (male or female) controls. Inhibitory activity was much higher in PPP from pregnant women than in PPP from controls, though it was comparable in platelet lysates both from pregnant women and from controls. The specific pregnancy Plasma-PA-I was present in high concentration in pregnancy PPP, but absent in PPP from the controls and also absent in platelet lysates from both pregnant women and controls. The results show that the specific pregnancy plasma-PA-I is not identical to either the PA-I in platelet lysate or to the PA-I in PPP from non-pregnant controls.
在孕妇和健康非孕（男性或女性）对照者的乏血小板血浆（PPP）、富血小板血浆（PRP）、血清和血小板裂解物中，检测了组织纤溶酶原激活物抑制剂（t-PA-I）以及与胎盘PA-I抗体反应的特异性妊娠血浆PA-I的含量。孕妇PPP中的抑制活性比对照者PPP中的高得多，不过孕妇和对照者血小板裂解物中的抑制活性相当。特异性妊娠血浆PA-I在妊娠PPP中浓度很高，但在对照者的PPP中不存在，在孕妇和对照者的血小板裂解物中也不存在。结果表明，特异性妊娠血浆PA-I既不同于血小板裂解物中的PA-I，也不同于非孕对照者PPP中的PA-I。
