From the Baylor College of Medicine, Division of Plastic Surgery; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School; Memorial Plastic Surgery; and Dallas Plastic Surgery Institute.
Plast Reconstr Surg. 2022 Jan 1;149(1):121e-129e. doi: 10.1097/PRS.0000000000008663.
Venous thromboembolism is a significant cause of postoperative death and morbidity. While prophylactic and treatment regimens exist, they usually come with some risk of clinically relevant bleeding and, thus, must be considered carefully for each individual patient.
This special topic article represents a review of current evidence regarding venous thromboembolism risk, biology, and prevention in plastic surgery patients. The specific types and duration of available prophylaxis are also reviewed. The balance of venous thromboembolism risk must be weighed against the risk of hemorrhage.
Though alternatives exist, the most validated risk assessment tool is the 2005 modification of the Caprini Risk Assessment Model. Controversies remain regarding recommendations for outpatient and low risk cosmetic patients. The authors additionally make recommendations for high-risk patients regarding the use of tranexamic acid, estrogen therapy, anesthesia, and prophylaxis regimens.
Our profession has made great strides in understanding the science behind venous thromboembolism, risk stratification for patients, and prophylactic regimens; yet, continued studies and definitive data are needed.
静脉血栓栓塞是术后死亡和发病的重要原因。虽然存在预防和治疗方案,但它们通常伴随着一定程度的临床相关出血风险,因此必须为每个患者仔细考虑。
这篇专题文章回顾了关于整形手术患者静脉血栓栓塞风险、生物学和预防的当前证据。还回顾了可用预防措施的具体类型和持续时间。必须权衡静脉血栓栓塞风险与出血风险之间的平衡。
尽管存在替代方案,但最有效的风险评估工具是 2005 年对 Caprini 风险评估模型的修改版。关于门诊和低风险美容患者的建议仍存在争议。作者还针对高风险患者提出了关于使用氨甲环酸、雌激素治疗、麻醉和预防方案的建议。
我们的专业在理解静脉血栓栓塞背后的科学、患者风险分层和预防方案方面取得了重大进展;然而,仍需要进一步的研究和明确的数据。