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严重冠状病毒疾病患者出院后的身体和肺部功能:基于聚类分析的初步横断面研究。

Physical and pulmonary capacities of individuals with severe coronavirus disease after hospital discharge: A preliminary cross-sectional study based on cluster analysis.

机构信息

Laboratorio de Estudos do Movimento, Instituto de Ortopedia e Traumatologia (IOT), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Programa de Graduacao em Ciencias do Envelhecimento, Universidade Sao Judas Tadeu (USJT), Sao Paulo, SP, BR.

出版信息

Clinics (Sao Paulo). 2021 Nov 26;76:e3540. doi: 10.6061/clinics/2021/e3540. eCollection 2021.

DOI:10.6061/clinics/2021/e3540
PMID:34852146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8595570/
Abstract

OBJECTIVE

This study aimed to analyze the physical and pulmonary capacities of hospitalized patients with severe coronavirus disease and its correlation with the time of hospitalization and complications involved.

METHODS

A total of 54 patients, aged ≥18 years of both sexes, were evaluated 2-4 months after hospital discharge in São Paulo, Brazil. The physical characteristics analyzed were muscle strength, balance, flexibility, and pulmonary function. The K-means cluster algorithm was used to identify patients with similar physical and pulmonary capacities, related to the time of hospitalization.

RESULTS

Two clusters were derived using the K-means algorithm. Patients allocated in cluster 1 had fewer days of hospitalization, intensive care, and intubation than those in cluster 2, which reflected a better physical performance, strength, balance, and pulmonary condition, even 2-4 months after discharge. Days of hospitalization were inversely related to muscle strength, physical performance, and lung function: hand grip D (r=-0.28, p=0.04), Short Physical Performance Battery score (r=-0.28, p=0.03), and forced vital capacity (r=-0.29, p=0.03).

CONCLUSION

Patients with a longer hospitalization time and complications progressed with greater loss of physical and pulmonary capacities.

摘要

目的

本研究旨在分析患有严重冠状病毒病的住院患者的身体和肺部能力及其与住院时间和所涉及并发症的相关性。

方法

在巴西圣保罗,对 54 名年龄≥18 岁的男女患者在出院后 2-4 个月进行了评估。分析的身体特征包括肌肉力量、平衡、柔韧性和肺功能。使用 K-均值聚类算法来识别具有相似身体和肺部能力的患者,这些能力与住院时间有关。

结果

使用 K-均值算法得出了两个聚类。与聚类 2 相比,聚类 1 中的患者住院、重症监护和插管天数更少,这反映了他们在出院后 2-4 个月的身体表现、力量、平衡和肺部状况更好。住院天数与肌肉力量、身体表现和肺功能呈负相关:握力 D(r=-0.28,p=0.04)、短体性能电池评分(r=-0.28,p=0.03)和用力肺活量(r=-0.29,p=0.03)。

结论

住院时间较长和并发症较多的患者的身体和肺部能力下降更为明显。

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