Departamento de Medicina Veterinária, Universidade Federal do Espírito Santo - UFES, Alegre, ES, Brasil.
Departamento de Parasitologia Animal, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro - UFRRJ, Seropédica, RJ, Brasil.
Rev Bras Parasitol Vet. 2021 Nov 29;30(4):e013121. doi: 10.1590/S1984-29612021089. eCollection 2021.
The objective of this study was to provide the first report of resistance of Haemonchus contortus to monepantel in sheep in Espírito Santo. The study was conducted in a property with history of monepantel use since 2014 and register of low efficacy in studies conducted over the past few years with fecal egg count reduction test. Lambs born on the property (males and females aged approximately 100 days) were selected and after eggs per gram of feces (EPG) analysis on fecal samples, these were divided into two groups: a group treated with monepantel (2.5 mg / Kg) and a control group without anthelmintic treatment. Seven days later, the animals were euthanized to recover parasites from the gastrointestinal tract. The efficacy of the treatment was 61.35% against H. contortus, thus proving that anthelmintic resistance to monepantel was present.
本研究的目的是首次报告在巴西圣埃斯皮里图州绵羊中旋毛虫对莫能菌素的耐药性。该研究在一个自 2014 年以来一直使用莫能菌素且近年来在粪便卵囊减少试验中疗效不佳的历史的农场进行。在该农场出生的羔羊（公母约 100 日龄）被选中，在对粪便样本进行每克粪便中的卵（EPG）分析后，将其分为两组：一组用莫能菌素（2.5mg / kg）处理，一组用驱虫药处理。七天后，动物被安乐死以从胃肠道中回收寄生虫。该治疗对旋毛虫的疗效为 61.35%，因此证明存在对莫能菌素的驱虫耐药性。
