Lince-Varela Rafael, Restrepo Diana, Lince Manuela, Muñoz David, Vásquez Federico, Quijano José M, Hincapié Laura, Hinestroza Juan F, Velásquez Mariana, Bedoya Juliana
Servicio de Cardiología Pediátrica, Clínica CardioVID, Medellín.
Facultad de Medicina, Universidad CES, Medellín.
Arch Cardiol Mex. 2021;91(4):422-430. doi: 10.24875/ACM.200003191.
Congenital heart diseases are the most common congenital abnormalities in newborns with a prevalence of 1%. Therapeutic and diagnostic cardiac catheterization has revolutionized the treatment of these diseases; however, it can be associated with complications.
To describe the incidence and type of complications associated with pediatric cardiac catheterization in a reference center for congenital heart defects.
Retrospective observational study, with analytical intention based on records of cardiac catheterization performed on patients with congenital and acquired heart disease.
2,688 records were included for nine consecutive years. 53.9% were men, 21.3% with ages between 2 and 5 years and 20.3% between 6 months and 2 years. 63.5% of the procedures were elective. The prevalence of complications in the first 24 hours after catheterization was 6.7% (4.2% minor and 2.4% major). Early death occurred in 0.8% of the procedures. Factors associated with complications were age at catheterization <28 days (OR 2.18, 95% CI .28-3.70]), precatheter oxygen saturation <79% (OR 2.15, 95% CI .02-4.53]), use of pre-catheter inotropics (OR 3.00, 95% CI .68-5.33]). The variables included in the model explain 38% of the variance of post-cardiac catheterization complications in patients younger than 18 years.
Cardiac catheterization is associated with major and minor complications including death. The associated factors were less than 28 days, lower oxygen saturation and use of pre-catheter inotropics.
先天性心脏病是新生儿中最常见的先天性异常,患病率为1%。治疗性和诊断性心导管插入术彻底改变了这些疾病的治疗方式;然而,它可能会引发并发症。
描述在一家先天性心脏缺陷参考中心,小儿心导管插入术相关并发症的发生率和类型。
回顾性观察研究,基于对先天性和后天性心脏病患者进行心导管插入术的记录进行分析。
连续九年纳入2688份记录。53.9%为男性,21.3%年龄在2至5岁之间,20.3%在6个月至2岁之间。63.5%的手术为择期手术。导管插入术后24小时内并发症的发生率为6.7%(轻度4.2%,重度2.4%)。0.8%的手术发生早期死亡。与并发症相关的因素包括导管插入时年龄<28天(比值比2.18,95%置信区间1.28 - 3.70)、导管插入前氧饱和度<79%(比值比2.15,95%置信区间1.02 - 4.53)、导管插入前使用正性肌力药物(比值比3.00,95%置信区间1.68 - 5.33)。该模型纳入的变量解释了18岁以下患者心导管插入术后并发症变异的38%。
心导管插入术会引发包括死亡在内的严重和轻微并发症。相关因素为年龄小于28天、较低的氧饱和度以及导管插入前使用正性肌力药物。