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Hyperkalemia with Mineralocorticoid Receptor Antagonist Use in People with CKD: Understanding and Mitigating the Risks.

作者信息

Epstein Murray, Pecoits-Filho Roberto, Clase Catherine M, Sood Manish M, Kovesdy Csaba P

机构信息

Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida.

Arbor Research Collaborative for Health, Ann Arbor, Michigan.

出版信息

Clin J Am Soc Nephrol. 2022 Mar;17(3):455-457. doi: 10.2215/CJN.13541021. Epub 2021 Dec 1.

DOI:10.2215/CJN.13541021
PMID:34853060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8975031/
Abstract
摘要

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The RALES Legacy and Finerenone Use on CKD Patients.RALES研究的遗产及非奈利酮在慢性肾脏病患者中的应用
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2
Ambulatory Treatments for RAAS Inhibitor-Related Hyperkalemia and the 1-Year Risk of Recurrence.门诊治疗 RAAS 抑制剂相关高钾血症及 1 年复发风险。
Clin J Am Soc Nephrol. 2021 Mar 8;16(3):365-373. doi: 10.2215/CJN.12990820. Epub 2021 Feb 19.
3
Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.非奈利酮对 2 型糖尿病患者慢性肾脏病结局的影响。
N Engl J Med. 2020 Dec 3;383(23):2219-2229. doi: 10.1056/NEJMoa2025845. Epub 2020 Oct 23.
4
Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.肾脏疾病中的钾离子稳态和血钾紊乱管理:KDIGO 争议会议的结论。
Kidney Int. 2020 Jan;97(1):42-61. doi: 10.1016/j.kint.2019.09.018. Epub 2019 Oct 10.
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Hyperkalemia constitutes a constraint for implementing renin-angiotensin-aldosterone inhibition: the widening gap between mandated treatment guidelines and the real-world clinical arena.高钾血症是实施肾素-血管紧张素-醛固酮抑制治疗的一个限制因素:这一限制因素导致既定治疗指南与现实临床领域之间的差距不断扩大。
Kidney Int Suppl (2011). 2016 Apr;6(1):20-28. doi: 10.1016/j.kisu.2016.01.004. Epub 2016 Mar 14.
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Evaluation of the treatment gap between clinical guidelines and the utilization of renin-angiotensin-aldosterone system inhibitors.肾素-血管紧张素-醛固酮系统抑制剂临床指南与使用情况之间治疗差距的评估
Am J Manag Care. 2015 Sep;21(11 Suppl):S212-20.
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Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial.新型非甾体盐皮质激素受体拮抗剂 BAY 94-8862 在慢性心力衰竭合并轻度或中度慢性肾脏病患者中的安全性和耐受性:一项随机、双盲试验。
Eur Heart J. 2013 Aug;34(31):2453-63. doi: 10.1093/eurheartj/eht187. Epub 2013 May 27.
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Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study.随机螺内酯评估研究发表后的高钾血症发生率。
N Engl J Med. 2004 Aug 5;351(6):543-51. doi: 10.1056/NEJMoa040135.