From the Department of Pharmaceutical Chemistry (Ahsan, Alhazmi, Najmi, Al Bratty); from the Department of Pharmaceutics (Javed), College of Pharmacy; from the Pharmacy Practice Research Unit (Syed, Makeen, Meraya, Albarraq, Alqahtani), Department of Clinical Pharmacy; from the College of Pharmacy (Alsraeya); and from the Substance Abuse and Toxicology Research Centre (Alhazmi), Jazan University, Jazan, Kingdom of Saudi Arabia.
Saudi Med J. 2021 Dec;42(12):1341-1352. doi: 10.15537/smj.2021.42.12.20210576.
To identify the self-reported vaccine-related side effects among healthcare professionals (HCPs) in the Jazan province, Saudi Arabia, and determine the associated socio-demographic factors. With the recent second and third waves of coronavirus disease -19 (COVID-19) infections worldwide, the race is not only to encourage but also to achieve mass vaccination.
A total of 397 HCPs from across Jazan province participated in an anonymous online cross-sectional survey conducted for a period of 45 days (March 30, 2021 to May 13, 2021) in Jazan province, Saudi Arabia. Data was collected using a validated 22-items self-report survey.
For both COVID-19 vaccines, majority of reports were related to flu-like symptoms including fever, chills, headache, fatigue, tiredness, and myalgia. Statistically significant associations were observed between the severity of side effects and gender (χ=73.32; <0.001), type of vaccine (χ=112.08; <0.001), and presence of known allergies (χ=99.69; <0.001). Female HCPs were more likely to report any side effects compared with male HCPs (adjusted odds ratio [AOR]: 3.72; <0.001). Furthermore, HCPs with known allergies were more likely to report any side effects than their counterparts with unknown allergies (AOR: 16.29; <0.001).
The findings of the present study would help in designing educational programs aimed at combating the misconstrued fear of vaccination and highlighting the urgent need of getting vaccinated. This study also helps in the identification of factors affecting the presence and severity of side effects.
在沙特阿拉伯吉赞省识别医疗保健专业人员（HCP）自我报告的疫苗相关副作用，并确定相关的社会人口因素。随着全球第二波和第三波 COVID-19 感染，竞赛不仅在于鼓励，还在于实现大规模疫苗接种。
在沙特阿拉伯吉赞省，共有 397 名 HCP 参加了一项为期 45 天（2021 年 3 月 30 日至 5 月 13 日）的匿名在线横断面调查。使用经过验证的 22 项自我报告调查收集数据。
对于两种 COVID-19 疫苗，大多数报告都与流感样症状有关，包括发烧、发冷、头痛、疲劳、疲倦和肌痛。副作用的严重程度与性别（χ=73.32；<0.001）、疫苗类型（χ=112.08；<0.001）和已知过敏史（χ=99.69；<0.001）之间存在统计学显著关联。与男性 HCP 相比，女性 HCP 更有可能报告任何副作用（调整后的优势比 [AOR]：3.72；<0.001）。此外，与没有过敏史的 HCP 相比，有已知过敏史的 HCP 更有可能报告任何副作用（AOR：16.29；<0.001）。
本研究的结果将有助于设计旨在消除疫苗接种误解恐惧并强调迫切需要接种疫苗的教育计划。这项研究还有助于确定影响副作用存在和严重程度的因素。
