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审视新冠疫苗安全性辩论。

Scrutinizing the COVID-19 vaccine safety debate.

作者信息

Bin Abdulrahman Khalid, Bin Abdulrahman Amro

机构信息

Department of Medical Education, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.

Preventive Medicine, Second Cluster, Ministry of Health, Riyadh, Saudi Arabia.

出版信息

Hum Vaccin Immunother. 2024 Dec 31;20(1):2401646. doi: 10.1080/21645515.2024.2401646. Epub 2024 Oct 29.

Abstract

The controversy surrounding the safety of coronavirus disease-19 vaccinations is part of a larger historical backdrop of ongoing discussions regarding vaccine safety that have spanned several decades. The historical disputes around measles, mumps, rubella, and influenza highlight the recurring pattern in which public doubt is fueled by false information and personal stories. A 2024 multinational study in the journal presented preexisting safety indicators for myocarditis, pericarditis, Guillain - Barré syndrome, and cerebral venous sinus thrombosis. The study had a notably large sample size and contributed to the ongoing discussion of vaccine safety. Examining this research clarifies the subtle distinctions between demonstrating causality and simple association, emphasizing the importance of thorough scientific investigation and open communication. The following recommendations should be prioritized to tackle vaccine hesitancy and ensure that politicians, healthcare practitioners, and public health officials make informed decisions. Vaccine safety data should be openly and readily provided to the public, particularly regarding potential hazards and advantages. Establishing post-marketing surveillance systems to monitor and examine adverse effects linked to vaccinations helps strengthen public confidence in the safety monitoring process and officials' dedication to addressing safety concerns with thoroughness.

摘要

围绕2019冠状病毒病疫苗安全性的争议,是关于疫苗安全性的持续讨论这一更大历史背景的一部分,这些讨论已持续了数十年。围绕麻疹、腮腺炎、风疹和流感的历史争议凸显了一种反复出现的模式,即虚假信息和个人故事加剧了公众的怀疑。2024年发表在某期刊上的一项多国研究提出了心肌炎、心包炎、吉兰-巴雷综合征和脑静脉窦血栓形成的预先存在的安全指标。该研究样本量显著庞大,为正在进行的疫苗安全性讨论做出了贡献。审视这项研究有助于厘清证明因果关系与简单关联之间的细微差别,强调全面科学调查和开放沟通的重要性。为应对疫苗犹豫并确保政治家、医疗从业者和公共卫生官员做出明智决策,应优先考虑以下建议。疫苗安全数据应向公众公开并随时提供,尤其是关于潜在危害和益处的数据。建立上市后监测系统以监测和检查与疫苗接种相关的不良反应,有助于增强公众对安全监测过程的信心以及官员们彻底解决安全问题的决心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b9d/11540079/79d7ab74fd30/KHVI_A_2401646_F0001_OC.jpg

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