Suppr超能文献

回顾性分析西班牙某急诊科急性非创伤性胸痛患者的 HEART 风险评分。

A retrospective HEART risk score comparation of acute non-traumatic chest pain patients in an emergency department in Spain.

机构信息

Centre d'Urgències d' Atenció Primària (CUAP) Lleida, Institut Català de la Salut (ICS), Av. Prat de la Riba, 56, 25004, Lleida, Spain.

Research Group in Therapies in Primary Care (GRETAPS), Lleida, Spain.

出版信息

Sci Rep. 2021 Dec 1;11(1):23268. doi: 10.1038/s41598-021-02682-5.

Abstract

Non traumatic chest pain is the second most common cause of attention at the Emergency Departments (ED). The objective is to compare the effectiveness of HEART risk score and the risk of having a Major Adverse Cardiovascular Event (MACE) during the following 6 weeks in 'Acute Non-traumatic Chest Pain' (ANTCP) patients of an ED in Lleida (Spain). The ANTCP patient cohort was defined using medical data from January 2015 to January 2016. A retrospective study was performed among 300 ANTCP patients. Diagnostic accuracy to predict MACE, HEART risk score effectiveness and patient risk stratification were analysed on the ANTCP Cohort. HEART risk score was conducted on ANTCP Cohort data and patients were stratified as low-risk (n = 116, 38.7%), moderate-risk (n = 164, 54.7%) and high-risk (n = 20, 6.7%); differently from the assessment performed by 'Current Emergency Department Guidelines' (CEDG) on the same patients: low risk and discharge (n = 56, 18.7%), medium risk and need of complementary tests (n = 137, 45.7%) and high risk and hospital admission (n = 107, 35.7%).The incidence of MACE was 2.5%, 20.7% and 100% in low, moderate and high-risk, respectively. Discrimination and accuracy indexes were moderate (AUC = 0.73, 95% confidence interval: 0.67-0.80). Clustering moderate-high risk groups by MACE incidence showed an 89.5% of sensitivity. Data obtained from this study suggests that HEART risk score stratified better 'acute non-traumatic chest pain' (ANTCP) patients in an Emergency Department (ED) compared with 'Current Emergency Department Guidelines' (CEDG) at the Hospital Universitari Arnau de Vilanova (HUAV). HEART score would reduce the number of subsequent consultations, unnecessary admissions and complementary tests.Trial registration: Retrospectively registered.

摘要

非创伤性胸痛是急诊科就诊的第二大常见原因。本研究旨在比较 HEART 风险评分在预测莱里达(西班牙)急诊科(ED)“急性非创伤性胸痛”(ANTCP)患者接下来 6 周内发生主要不良心血管事件(MACE)的有效性。ANTCP 患者队列使用 2015 年 1 月至 2016 年 1 月的医疗数据进行定义。对 300 名 ANTCP 患者进行回顾性研究。对 ANTCP 队列进行诊断准确性分析、HEART 风险评分有效性分析和患者风险分层分析。HEART 风险评分对 ANTCP 队列数据进行分析,患者分层为低危(n=116,38.7%)、中危(n=164,54.7%)和高危(n=20,6.7%);与同一患者的“现行急诊科指南”(CEDG)评估不同:低危和出院(n=56,18.7%)、中危和需要补充检查(n=137,45.7%)和高危和住院(n=107,35.7%)。低危、中危和高危患者的 MACE 发生率分别为 2.5%、20.7%和 100%。判别和准确性指标中等(AUC=0.73,95%置信区间:0.67-0.80)。根据 MACE 发生率对中高危风险组进行聚类,显示出 89.5%的敏感性。本研究的数据表明,与医院大学医院阿努乌·德·比拉诺瓦(HUAV)的“现行急诊科指南”(CEDG)相比,HEART 风险评分对急诊科(ED)“急性非创伤性胸痛”(ANTCP)患者的分层更好。HEART 评分可减少随后的就诊次数、不必要的住院和补充检查。

试验注册

回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15c6/8636492/205eade32b87/41598_2021_2682_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验