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本文引用的文献

1
Biomarkers for hepatocellular carcinoma based on body fluids and feces.基于体液和粪便的肝细胞癌生物标志物。
World J Gastrointest Oncol. 2021 May 15;13(5):351-365. doi: 10.4251/wjgo.v13.i5.351.
2
Exosome in Hepatocellular Carcinoma: an update.肝细胞癌中的外泌体:最新进展
J Cancer. 2021 Mar 5;12(9):2526-2536. doi: 10.7150/jca.54566. eCollection 2021.
3
Biomarkers for hepatocellular cancer.肝细胞癌的生物标志物
World J Hepatol. 2020 Sep 27;12(9):558-573. doi: 10.4254/wjh.v12.i9.558.
4
Circulating biomarkers for early detection of hepatocellular carcinoma.用于肝细胞癌早期检测的循环生物标志物。
Therap Adv Gastroenterol. 2020 Jun 29;13:1756284820931734. doi: 10.1177/1756284820931734. eCollection 2020.
5
The Microbiome and Hepatocellular Carcinoma.微生物组与肝细胞癌。
Liver Transpl. 2020 Oct;26(10):1316-1327. doi: 10.1002/lt.25828. Epub 2020 Aug 9.
6
Biomarkers in Hepatocellular Carcinoma: Diagnosis, Prognosis and Treatment Response Assessment.肝细胞癌的生物标志物:诊断、预后和治疗反应评估。
Cells. 2020 Jun 1;9(6):1370. doi: 10.3390/cells9061370.
7
Identification of noninvasive diagnostic biomarkers for hepatocellular carcinoma by urinary proteomics.尿蛋白质组学鉴定肝细胞癌的非侵入性诊断生物标志物。
J Proteomics. 2020 Aug 15;225:103780. doi: 10.1016/j.jprot.2020.103780. Epub 2020 Apr 13.
8
Mouse Models for Immunotherapy in Hepatocellular Carcinoma.肝细胞癌免疫治疗的小鼠模型
Cancers (Basel). 2019 Nov 15;11(11):1800. doi: 10.3390/cancers11111800.
9
Genetic Biomarkers For Hepatocellular Carcinoma In The Era Of Precision Medicine.精准医学时代的肝细胞癌基因生物标志物
J Hepatocell Carcinoma. 2019 Oct 18;6:151-166. doi: 10.2147/JHC.S224849. eCollection 2019.
10
Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis.全面代谢组学搜索用于区分早期肝细胞癌与肝硬化的生物标志物
Cancers (Basel). 2019 Oct 6;11(10):1497. doi: 10.3390/cancers11101497.

肝细胞癌生物标志物,迫在眉睫的需求。

Hepatocellular carcinoma biomarkers, an imminent need.

作者信息

Zamora-León S Pilar

机构信息

Department of Preclinical Sciences, Faculty of Medicine, Universidad Católica del Maule, Talca 3460000, Chile.

出版信息

World J Gastrointest Oncol. 2021 Nov 15;13(11):1847-1849. doi: 10.4251/wjgo.v13.i11.1847.

DOI:10.4251/wjgo.v13.i11.1847
PMID:34853655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8603452/
Abstract

Hepatocellular carcinoma (HCC) is the most common malignant neoplasm of the liver and one of the deadliest cancers worldwide. The identification of novel, highly specific and more sensitive biomarkers for HCC is crucial because existing ones are deficient and non-confirmatory without histological biopsy or imaging techniques.

摘要

肝细胞癌(HCC)是肝脏最常见的恶性肿瘤,也是全球最致命的癌症之一。识别新型、高度特异性且更敏感的HCC生物标志物至关重要,因为现有的生物标志物存在缺陷,在没有组织活检或成像技术的情况下无法得到证实。