Jo Noah Y, Chu Chu-Chiao, Ramsey Bryan C
Internal Medicine, Brooke Army Medical Center, Fort Sam Houston, USA.
Cardiology, Brooke Army Medical Center, Fort Sam Houston, USA.
Cureus. 2021 Oct 26;13(10):e19058. doi: 10.7759/cureus.19058. eCollection 2021 Oct.
Brugada electrocardiogram (ECG) pattern describes a characteristic right bundle branch block (RBBB) appearance with persistent ST-segment elevation in precordial leads V1 to V3, often associated with Brugada syndrome, a genetic sodium channelopathy, in the absence of ischemic or structural heart disease. Known triggers such as fever, electrolyte abnormalities, medications, or recreational drugs may elicit such an ECG pattern without a clear clinical significance yet creating a dilemma for clinicians providing care in the urgent setting. We present a case of reversible Brugada electrocardiogram pattern (BEP) after recreational use of delta-8-tetrahydrocannabinol (THC) and explore the need for further research on the safety of such an over-the-counter supplement.
Brugada心电图（ECG）模式描述了一种特征性的右束支传导阻滞（RBBB）表现，即胸前导联V1至V3出现持续性ST段抬高，常在无缺血性或结构性心脏病的情况下与Brugada综合征（一种遗传性钠通道病）相关。已知的诱因如发热、电解质异常、药物或消遣性药物可能引发这种ECG模式，但其临床意义尚不明确，这给在紧急情况下提供护理的临床医生带来了难题。我们报告一例在消遣性使用δ-8-四氢大麻酚（THC）后出现可逆性Brugada心电图模式（BEP）的病例，并探讨对这种非处方补充剂安全性进行进一步研究的必要性。
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