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一份棘手的心电图:可卡因诱发的2型Brugada综合征拟表型

A tricky electrocardiogram: cocaine induced Brugada type 2 phenocopy.

作者信息

Zampi Giordano, Pergolini Amedeo, Pontillo Daniele, Sommariva Luigi

机构信息

Department of Cardiology, Belcolle Hospital Viterbo, Italy.

Department of Cardiovascular Science "S. Camillo-Forlanini" Hospital Rome, Italy.

出版信息

Am J Cardiovasc Dis. 2020 Jun 15;10(2):131-135. eCollection 2020.

Abstract

BACKGROUND

The pharmacological effects of cocaine have been associated with different types of cardiac dysrhythmias and with Brugada pattern on the ECG, but currently only type 1 pattern has been described. We report a case of a transient Brugada type 2 pattern in a young cocaine abuser.

METHOD

We report the clinical presentation of a 32-year-old male with a history of cocaine abuse.

RESULT

The treatment and the resolution of the acute phase have been described; moreover we discuss the pathophysiology of the Brugada phenocopy in this specificclinical setting.

CONCLUSION

The clinical impact of our case report underscores the necessity of prompt physician awareness of any ECG abnormality besides myocardial infarction in patients with cocaine abuse, such as any Brugada pattern, which could lead to ominous ventricular arrhythmias.

摘要

背景

可卡因的药理作用与不同类型的心律失常以及心电图上的 Brugada 波型有关,但目前仅描述了 1 型波型。我们报告了一名年轻可卡因滥用者出现短暂性 Brugada 2 型波型的病例。

方法

我们报告了一名有可卡因滥用史的 32 岁男性的临床表现。

结果

描述了急性期的治疗及病情缓解情况;此外,我们讨论了在这种特定临床情况下 Brugada 拟表型的病理生理学。

结论

我们病例报告的临床意义强调,对于可卡因滥用患者,除心肌梗死外,医生必须迅速意识到任何心电图异常,如任何 Brugada 波型,因为这可能导致恶性室性心律失常。

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本文引用的文献

1
Brugada Phenocopy Induced by Recreational Drug Use.由娱乐性药物使用诱发的Brugada综合征拟表型
Case Rep Cardiol. 2018 Apr 11;2018:6789253. doi: 10.1155/2018/6789253. eCollection 2018.
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Brugada syndrome.布加综合征
Methodist Debakey Cardiovasc J. 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25.
4
Brugada phenocopy in concomitant ethanol and heroin overdose.乙醇和海洛因同时过量导致的Brugada综合征拟表型
Ann Noninvasive Electrocardiol. 2015 Jan;20(1):87-90. doi: 10.1111/anec.12171. Epub 2014 Jun 5.
5
6
Brugada phenocopy: new terminology and proposed classification.Brugada综合征拟表型:新术语及拟分类
Ann Noninvasive Electrocardiol. 2012 Oct;17(4):299-314. doi: 10.1111/j.1542-474X.2012.00525.x. Epub 2012 Aug 13.

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