Section of Diagnostic Imaging, Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
J Med Imaging Radiat Oncol. 2022 Oct;66(7):940-945. doi: 10.1111/1754-9485.13363. Epub 2021 Dec 1.
The objective of this study was to compare the frequency and entity, in computed tomography (CT) urography, of streak artefacts on the urinary tract generated by two contrast agents with a different iodine concentration and osmolarity.
Computed tomography scans including an excretory renal phase, performed on adult subjects in the period May-July 2020, were retrospectively evaluated in consensus by three expert radiologists, to detect any streak artefacts located in the urinary tract. Patients were administered either 1.6 mL/kg of Iodixanol 320 mgI/mL or 1.3 mL/kg of Iomeprol 400 mgI/mL.
In total, 144 CT scans were analysed, subdivided into two groups administered either Iodixanol (71/144 (49.3%) patients) or Iomeprol (73/144 (50.7%) patients). In 41% cases, no beam hardening artefacts were found; among these, 12/59 (20.3%) patients had received Iodixanol and 47/59 (79.7%) Iomeprol. In the Iodixanol group, the mean contrast density on the renal pelvis was 2565.6 HU and streak artefacts occurred in 59/71 cases (83.1%); in 33/59 (55.9%) cases, the artefacts were marked, and in 26/59 (44.1%) minimal. In the Iomeprol group, the mean contrast density on the renal pelvis was 1666 HU and streak artefacts occurred in 26/73 cases (35.6%); in 7/26 (27%) cases, the artefacts were marked and in 19/26 (73%) minimal.
The study data demonstrate a significant difference in the attenuation values of iodine urine in the excretory system between the Iodixanol and Iomeprol group. Iodixanol induced a higher frequency and burden of artefacts, compared to Iomeprol.
本研究的目的是比较两种不同碘浓度和渗透压的对比剂在 CT 尿路造影中对尿路条纹伪影的产生频率和程度。
对 2020 年 5 月至 7 月间进行的成人 CT 扫描进行回顾性评估，由三位专家放射科医生进行共识评估，以检测位于尿路的任何条纹伪影。患者分别接受 1.6mL/kg 的碘克沙醇 320mgI/mL 或 1.3mL/kg 的碘美普尔 400mgI/mL。
共分析了 144 例 CT 扫描，分为碘克沙醇组（71/144[49.3%]患者）和碘美普尔组（73/144[50.7%]患者）。在 41%的病例中未发现束硬化伪影；其中，12/59（20.3%）患者接受了碘克沙醇，47/59（79.7%）患者接受了碘美普尔。在碘克沙醇组，肾盂的平均对比密度为 2565.6HU，条纹伪影发生在 59/71 例（83.1%）；33/59（55.9%）例为显著，26/59（44.1%）例为轻微。在碘美普尔组，肾盂的平均对比密度为 1666HU，条纹伪影发生在 26/73 例（35.6%）；7/26（27%）例为显著，19/26（73%）例为轻微。
研究数据表明，碘尿在排泄系统中的衰减值在碘克沙醇组和碘美普尔组之间存在显著差异。与碘美普尔相比，碘克沙醇导致条纹伪影的发生频率和程度更高。
