Department of Cardiology Copenhagen University Hospital Herlev and Gentofte Hellerup Denmark.
Department of Cardiology Nordsjaellands Hospital Hillerød Denmark.
J Am Heart Assoc. 2021 Dec 7;10(23):e021827. doi: 10.1161/JAHA.121.021827. Epub 2021 Dec 2.
Background It remains challenging to identify patients at risk of out-of-hospital cardiac arrest (OHCA). We aimed to examine health care contacts in patients before OHCA compared with the general population that did not experience an OHCA. Methods and Results Patients with OHCA with a presumed cardiac cause were identified from the Danish Cardiac Arrest Registry (2001-2014) and their health care contacts (general practitioner [GP]/hospital) were examined up to 1 year before OHCA. In a case-control study (1:9), OHCA contacts were compared with an age- and sex-matched background population. Separately, patients with OHCA were examined by the contact type (GP/hospital/both/no contact) within 2 weeks before OHCA. We included 28 955 patients with OHCA. The weekly percentages of patient contacts with GP the year before OHCA were constant (25%) until 1 week before OHCA when they markedly increased (42%). Weekly percentages of patient contacts with hospitals the year before OHCA gradually increased during the last 6 months (3.5%-6.6%), peaking at the second week (6.8%) before OHCA; mostly attributable to cardiovascular diseases (21%). In comparison, there were fewer weekly contacts among controls with 13% for GP and 2% for hospital contacts (<0.001). Within 2 weeks before OHCA, 57.8% of patients with OHCA had a health care contact, and these patients had more contacts with GP (odds ratio [OR], 3.17; 95% CI, 3.09-3.26) and hospital (OR, 2.32; 95% CI, 2.21-2.43) compared with controls. Conclusions The health care contacts of patients with OHCA nearly doubled leading up to the OHCA event, with more than half of patients having health care contacts within 2 weeks before arrest. This could have implications for future preventive strategies.
识别院外心脏骤停(OHCA)高危患者仍然具有挑战性。我们旨在比较 OHCA 患者与未发生 OHCA 的一般人群在 OHCA 前的医疗接触情况。
从丹麦心脏骤停登记处(2001-2014 年)中确定了推定由心脏原因引起的 OHCA 患者,并在 OHCA 前 1 年内检查了他们的医疗接触情况(全科医生/医院)。在病例对照研究(1:9)中,将 OHCA 接触者与年龄和性别匹配的背景人群进行比较。此外,还通过 OHCA 前 2 周内的接触类型(全科医生/医院/两者/无接触)对 OHCA 患者进行了检查。我们纳入了 28955 名 OHCA 患者。OHCA 前 1 年每周与全科医生接触的患者百分比保持不变(25%),直到 OHCA 前 1 周时显著增加(42%)。OHCA 前 1 年每周与医院接触的患者百分比逐渐增加,在过去 6 个月内增加(3.5%-6.6%),在 OHCA 前第 2 周达到高峰(6.8%);主要归因于心血管疾病(21%)。相比之下,对照组每周与全科医生的接触次数较少,为 13%,与医院的接触次数较少,为 2%(<0.001)。在 OHCA 前 2 周内,57.8%的 OHCA 患者有医疗接触,与对照组相比,这些患者与全科医生(比值比 [OR],3.17;95%CI,3.09-3.26)和医院(OR,2.32;95%CI,2.21-2.43)的接触更多。
OHCA 患者的医疗接触几乎翻了一番,在 OHCA 事件发生前的最后一周,超过一半的患者在逮捕前 2 周内有医疗接触。这可能对未来的预防策略产生影响。