Nabavizadeh Seyed Hesamedin, Mehdizadegan Nima, Moeini Mohsen, Alyasin Soheila, Esmaeilzadeh Hossein, Askarisarvestani Aida
Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Division of Pediatric Cardiology, Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Pediatr Cardiol. 2022 Apr;43(4):816-820. doi: 10.1007/s00246-021-02792-x. Epub 2021 Dec 2.
Kawasaki disease is an acute systemic vasculitis which can cause cardiac involvement among other symptoms. In this study we aimed to assess the relationship between the echocardiographic findings of Kawasaki disease with the clinical and paraclinical findings of the patients. In this cross-sectional study, the symptoms of 307 Kawasaki patients were registered and the association of the symptoms with paraclinical findings and echocardiographic studies was assessed. 190 (61.9%) of the patients were male and 117 (38.1%) were female. 193 patients (62.9%) did not have any abnormalities in their echocardiography, while others showed coronary artery aneurysms, perivascular brightness, coronary artery dilatation, and trivial Mitral Regurgitation in their echocardiography. A significant inverse relationship was seen with echocardiographic findings and age. Thrombocytosis, conjunctivitis, and oral and/or pharyngeal erythema and/or strawberry tongue were associated with higher rates of echocardiographic abnormalities. Echocardiographic abnormalities are associated with younger age, higher platelets, and the existence of conjunctivitis and oral and/or pharyngeal erythema and/or strawberry tongue.
川崎病是一种急性全身性血管炎,除其他症状外还可导致心脏受累。在本研究中,我们旨在评估川崎病的超声心动图表现与患者临床及辅助检查结果之间的关系。在这项横断面研究中,记录了307例川崎病患者的症状,并评估了这些症状与辅助检查结果及超声心动图检查之间的关联。患者中190例(61.9%)为男性,117例(38.1%)为女性。193例患者(62.9%)超声心动图无任何异常,而其他患者超声心动图显示有冠状动脉瘤、血管周围亮度增加、冠状动脉扩张及轻度二尖瓣反流。超声心动图表现与年龄呈显著负相关。血小板增多、结膜炎、口腔和/或咽部红斑和/或草莓舌与超声心动图异常的发生率较高相关。超声心动图异常与年龄较小、血小板计数较高以及存在结膜炎、口腔和/或咽部红斑和/或草莓舌有关。